Insight into structure and function of Dicer-related helicases from Caenorhabditis elegans

• المؤلف الرئيسي: Li, Kuohan
• مؤلفون آخرون: Daniela Rhodes
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2019
• الموضوعات: Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/96068; http://hdl.handle.net/10220/49480
• المؤسسة: Nanyang Technological University

RNA interference (RNAi) is a major antiviral defense mechanism in nematodes. In Caenorhabditis elegans (C. elegans), Dicer-related helicase 1 (DRH-1) acts to enhance the production of primary virus-derived small interfering RNA (siRNA) in antiviral RNAi pathway. However, Dicer-related helicase 3 (DR...