Crystal structure of 70S ribosome with both cognate tRNAs in the E and P sites representing an authentic elongation complex

• المؤلفون الرئيسيون: Feng, Shu, Chen, Yun, Gao, Yong-Gui
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Science::Biological sciences::Microbiology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/96532; http://hdl.handle.net/10220/9877

During the translation cycle, a cognate deacylated tRNA can only move together with the codon into the E site. We here present the first structure of a cognate tRNA bound to the ribosomal E site resulting from translocation by EF-G, in which an entire L1 stalk (L1 protein and L1 rRNA) interacts wi...