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__    __     ___      _  __     ___     __   _   
\ \\ / //   / _ \\   | |/ //   / _ \\  | || | || 
 \ \/ //   / //\ \\  | ' //   | / \ || | '--' || 
  \  //   |  ___  || | . \\   | \_/ || | .--. || 
   \//    |_||  |_|| |_|\_\\   \___//  |_|| |_|| 
    `     `-`   `-`  `-` --`   `---`   `-`  `-`

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Text this: Why is F19Ap53 unable to bind MDM2? Simulations suggest crack propagation modulates binding