Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

10.1186/1476-4598-13-66

Saved in:

書目詳細資料
Main Authors:	Sethi, G., Chatterjee, S., Rajendran, P., Li, F., Shanmugam, M.K., Wong, K.F., Kumar, A.P., Senapati, P., Behera, A.K., Hui, K.M., Basha, J., Natesh, N., Luk, J.M., Kundu, T.K.
其他作者:	PHARMACOLOGY
格式:	Article
出版:	2014
主題:	Acetylation Apoptosis Garcinol HCC STAT3
在線閱讀:	http://scholarbank.nus.edu.sg/handle/10635/109416
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!
機構:	National University of Singapore

相似書籍

TARGETED INHIBITION OF CONSTITUTIVE AND INTERLEUKIN-6-INDUCIBLE STAT3 SIGNALING CASCADE FOR THE PREVENTION AND TREATMENT OF HEAD AND NECK SQUAMOUS CELL CARCINOMA
由: LI FENG
出版: (2015)

Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers
由: Li F., et al.
出版: (2020)

Activation of STAT3 and STAT5 signaling in epithelial ovarian cancer progression: Mechanism and therapeutic opportunity
由: Wu, C.-J., et al.
出版: (2021)

Garcinol, a polyisoprenylated benzophenone modulates multiple proinfl ammatory signaling cascades leading to the suppression of growth and survival of head and neck carcinoma
由: Li, F., et al.
出版: (2014)

Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells
由: Li, F., et al.
出版: (2011)

ROLE OF TISSUE-SPECIFIC STAT PROTEINS IN TUMOR AND AUTOIMMUNITY
由: YANG FAN
出版: (2016)

Brusatol suppresses STAT3-driven metastasis by downregulating epithelial-mesenchymal transition in hepatocellular carcinoma
由: Lee, J.H., et al.
出版: (2021)

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3
由: Subramaniam, A., et al.
出版: (2014)

γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: Potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent
由: Rajendran, P., et al.
出版: (2014)

Multiple roles of STAT3 in cardiovascular inflammatory responses
由: Lim, C.P., et al.
出版: (2014)

Acetylated lignin from oil palm empty fruit bunches and its electrospun nanofibres with PVA: potential carbon fibre precursor
由: Harahap, Mahyuni, et al.
出版: (2023)

Signal transducer and activator of transcription (STATs) proteins in cancer and inflammation: Functions and therapeutic implication
由: Loh, C.-Y., et al.
出版: (2021)

Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells
由: Kannaiyan, R., et al.
出版: (2014)

Role of stat3 in cell migration
由: TENG TERK SHIN
出版: (2011)

Novel 1,3,4-oxadiazole targets STAT3 signaling to induce antitumor effect in lung cancer
由: Malojirao, V.H., et al.
出版: (2021)

Involvement of STAT5 in oncogenesis
由: Halim, C.E., et al.
出版: (2021)

Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma
由: Subramaniam, A., et al.
出版: (2014)

Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening
由: Leung, Ka-Ho, et al.
出版: (2016)

Elevated acetyl-CoA by amino acid recycling fuels microalgal neutral lipid accumulation in exponential growth phase for biofuel production
由: Yao L., et al.
出版: (2020)

Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin
由: Zhou, J., et al.
出版: (2011)

Targeting the STAT3 signaling pathway in cancer: Role of synthetic and natural inhibitors
由: Sikka, S., et al.
出版: (2014)

Targeting STAT3 and oxidative phosphorylation in oncogene-addicted tumors
由: Lee M., et al.
出版: (2020)

Low-capacitance StatCom with modular inductive filter
由: Farivar, Glen, et al.
出版: (2020)

STAT3 Regulates Mouse Neural Progenitor Proliferation and Differentiation by Promoting Mitochondrial Metabolism
由: Su, Y., et al.
出版: (2021)

Sirt1 antagonizes Stra13 Mediated p53 Acetylation and Senescence
由: TAN YONG HUA
出版: (2014)

Attenuation of STAT3 signaling cascade by daidzin can enhance the apoptotic potential of bortezomib against multiple myeloma
由: Yang, M.H., et al.
出版: (2021)

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins
由: Subramaniam, A., et al.
出版: (2014)

Improving acetyl-CoA biosynthesis in Saccharomyces cerevisiae via the overexpression of pantothenate kinase and PDH bypass
由: Liu, Wenshan, et al.
出版: (2018)

Nanoparticles Targeting STATs in Cancer Therapy
由: Ashrafizadeh, M., et al.
出版: (2021)

Brusatol, a nrf2 inhibitor targets stat3 signaling cascade in head and neck squamous cell carcinoma
由: Rangappa, K.S., et al.
出版: (2021)

The IκB kinase inhibitor ACHP targets the STAT3 signaling pathway in human non-small cell lung carcinoma cells
由: Lee, J.H., et al.
出版: (2021)

Stat3 contributes to keloid pathogenesis via promoting collagen production, cell proliferation and migration
由: Lim, C.P., et al.
出版: (2014)

Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK)
由: Jain, N., et al.
出版: (2014)

Anti-myeloma effects of icariin are mediated through the attenuation of JAK/STAT3-dependent signaling cascade
由: Jung Y.Y., et al.
出版: (2019)

Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness
由: De La Iglesia N., et al.
出版: (2018)

ROLE OF NOTCH AND JAK/STAT SIGNALING PATHWAYS IN ACUTE MEGAKARYOBLASTIC LEUKEMIA
由: KELLY ONG OOI KEE
出版: (2015)

โปรแกรมคำนวณภาวะโภชนาการ (INMU – NutriStat)
由: อุไรพร จิตต์แจ้ง
出版: (2020)

γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model
由: Siveen, K.S., et al.
出版: (2014)

Properties and Macromolecular Structure of Unacetylated and Acetylated Nata de Coco
由: Cuyegkeng, Ma. Assunta C, et al.
出版: (1997)

STAT3 Localizes in Mitochondria-Associated ER Membranes Instead of in Mitochondria
由: Su, Y., et al.
出版: (2021)