Computer aided drug design: Drug target directed in silico approaches

Computer aided drug design: Drug target directed in silico approaches

Ph.D

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	CHEN XIN
مؤلفون آخرون:	COMPUTATIONAL SCIENCE
التنسيق:	Theses and Dissertations
اللغة:	English
منشور في:	2010
الموضوعات:	Computer aided drug design, Drug target, Database design, Statistical learning, Virtual screening, Docking.
الوصول للمادة أونلاين:	http://scholarbank.nus.edu.sg/handle/10635/13687
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة

In-silico approaches to multi-target drug discovery computer aided multi-target drug design, multi-target virtual screening
بواسطة: Ma, X.H., وآخرون
منشور في: (2014)

Recent advances in computer-aided drug design
بواسطة: Song, C.M., وآخرون
منشور في: (2011)

Role of computer-aided drug design in modern drug discovery
بواسطة: Macalino, Stephani Joy Y., وآخرون
منشور في: (2015)

Increasing the odds of drug hit identification by screening against receptor homologs?
بواسطة: Ji, Z.L., وآخرون
منشور في: (2014)

Combinatorial support vector machines approach for virtual screening of selective multi-target serotonin reuptake inhibitors from large compound libraries
بواسطة: Shi, Z., وآخرون
منشور في: (2014)

Learning the drug target-likeness of a protein
بواسطة: Xu, H., وآخرون
منشور في: (2014)

Does drug-target have a likeness?
بواسطة: Xu, H., وآخرون
منشور في: (2014)

Expediting the design, discovery and development of anticancer drugs using computational approaches
بواسطة: Basith, Shaherin, وآخرون
منشور في: (2017)

Protein language models are performant in structure-free virtual screening
بواسطة: Lam, Hilbert Yuen In, وآخرون
منشور في: (2024)

Targeting the sphingosine 1-phosphate receptor 2 for multiple sclerosis computer-aided drug discovery
بواسطة: Dalmacio, Jeremy V., وآخرون
منشور في: (2022)

A support vector machines approach for virtual screening of active compounds of single and multiple mechanisms from large libraries at an improved hit-rate and enrichment factor
بواسطة: Han, L.Y., وآخرون
منشور في: (2014)

STRUCTURE-BASED COMPUTATIONAL MODELING OF PROTEIN-LIGAND INTERACTIONS - APPLIED TO PROTEINS INVOLVED IN HUMAN DISEASES
بواسطة: SRDAN MASIREVIC
منشور في: (2022)

Ligand - Protein inverse docking and its potential use in the computer search of protein targets of a small molecule
بواسطة: Chen, Y.Z., وآخرون
منشور في: (2016)

Identifying novel type ZBGs and nonhydroxamate HDAC inhibitors through a SVM based virtual screening approach
بواسطة: Liu, X.H., وآخرون
منشور في: (2014)

Virtual Screening of Multi-Target Agents by Combinatorial Machine Learning Methods
بواسطة: SHI ZHE
منشور في: (2012)

Molecular similarity and diversity approaches in chemoinformatics
بواسطة: Khanna, V., وآخرون
منشور في: (2014)

Comparative analysis of machine learning methods in ligand-based virtual screening of large compound libraries
بواسطة: Ma, X.H., وآخرون
منشور في: (2011)

Finding new molecular targets of familiar natural products using in silico target prediction
بواسطة: Mayr, F., وآخرون
منشور في: (2021)

Prediction of potential toxicity and side effect protein targets of a small molecule by a ligand-protein inverse docking approach
بواسطة: Chen, Y.Z., وآخرون
منشور في: (2014)

Inhibitor prediction by machine learning approaches
بواسطة: YAO LIXIA
منشور في: (2010)

Virtual screening of selective multitarget kinase inhibitors by combinatorial support vector machines
بواسطة: Ma, X.H., وآخرون
منشور في: (2014)

A Rational Workflow for Sequential Virtual Screening of Chemical Libraries on Searching for New Tyrosinase Inhibitors
بواسطة: Le, Thi Thu Huong
منشور في: (2016)

Development Of Database And Computational Methods For Disease Detection And Drug Discovery
بواسطة: HAN BUCONG
منشور في: (2013)

In Silico Methodologies for Selection and Prioritization of Compounds in Drug Discovery
بواسطة: YEO WEE KIANG
منشور في: (2013)

Statistical learning approaches for predicting pharmacological properties of pharmaceutical agents
بواسطة: LI HU
منشور في: (2010)

Development and experimental test of support vector machines virtual screening method for searching Src inhibitors from large compound libraries
بواسطة: Han, B., وآخرون
منشور في: (2014)

The Therapeutic Target Database: An Internet resource for the primary targets of approved, clinical trial and experimental drugs
بواسطة: Liu, X., وآخرون
منشور في: (2014)

Effect of training data size and noise level on support vector machines virtual screening of genotoxic compounds from large compound libraries
بواسطة: Kumar, P., وآخرون
منشور في: (2014)

The antimalarial drug dihydroartemisinin: Formulation design and challenges in drug development
بواسطة: Satit Puttipipatkhachorn, وآخرون
منشور في: (2020)

Trends in the exploration of therapeutic targets for the treatment of endocrine, metabolic and immune disorders
بواسطة: Chen, X., وآخرون
منشور في: (2014)

Information of ADME-associated proteins and potential application for pharmacogenetic prediction of drug responses
بواسطة: Zheng, C.J., وآخرون
منشور في: (2014)

Drug ADME-associated protein database as a resource for facilitating pharmacogenomics research
بواسطة: Zheng, C.J., وآخرون
منشور في: (2014)

Integrin targeted drug and gene delivery
بواسطة: Wang, Z., وآخرون
منشور في: (2014)

Developing antiangiogenic peptide drugs for angiogenesis-related diseases
بواسطة: Sulochana, K.N., وآخرون
منشور في: (2014)

Application of support vector machines to in silico prediction of cytochrome P450 enzyme substrates and inhibitors
بواسطة: Yap, C.W., وآخرون
منشور في: (2014)

A Harm Reduction Approach to HIV/AIDS and Drug Use in Malaysia
بواسطة: Jade Goh
منشور في: (2020)

Computational study of therapeutic targets and ADME-Associated proteins and application in drug design
بواسطة: ZHENG CHANJUAN
منشور في: (2014)

In silico genome-scale modeling and analysis for identifying anti-tubercular drug targets
بواسطة: Lee, D.-Y., وآخرون
منشور في: (2014)

Drug interaction of rifampicin on fluconazole in AIDS patients : pharmacokinetics and clinical observations
بواسطة: Nawarat Thanompuangseree
منشور في: (2010)

Design without boundaries: Computer aided design (CAD) and graphic information systems on the web
بواسطة: Guingao, Jojo
منشور في: (1998)