Corticosteroids for Dengue - Why Don't They Work?

• Main Authors: Nguyen T.H.T., Nguyen T.H.Q., Vu T.T., Farrar J., Hoang T.L., Dong T.H.T., Ngoc Tran V., Phung K.L., Wolbers M., Whitehead S.S., Hibberd M.L., Wills B., Simmons C.P.
• Other Authors: SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
• Format: Article
• Published: 2019
• Subjects: corticosteroid; gamma interferon; interleukin 10; interleukin 12p70; interleukin 13; interleukin 1beta; interleukin 2; interleukin 4; interleukin 5; interleukin 6; placebo; prednisolone; tumor necrosis factor alpha; adolescent; article; child; controlled study; dengue; drug megadose; female; gene expression; human; immune response; immunoassay; low drug dose; male; microarray analysis; polymerase chain reaction; randomized controlled trial; school child; Adolescent; Child; Child, Preschool; Cytokines; Dengue; Female; Gene Expression Profiling; Humans; Immunologic Factors; Immunomodulation; Killer Cells, Natural; Male; Placebos; Prednisolone; T-Lymphocytes, Cytotoxic; Treatment Failure; Vietnam; Young Adult
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161626
• Institution: National University of Singapore

10.1371/journal.pntd.0002592