Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma

Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma

10.1371/journal.pgen.1002654

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Bibliographic Details
Main Authors:	Wiggs J.L., Yaspan B.L., Hauser M.A., Kang J.H., Allingham R.R., Olson L.M., Abdrabou W., Fan B.J., Wang D.Y., Brodeur W., Budenz D.L., Caprioli J., Crenshaw A., Crooks K., DelBono E., Doheny K.F., Friedman D.S., Gaasterland D., Gaasterland T., Laurie C., Lee R.K., Lichter P.R., Loomis S., Liu Y., Medeiros F.A., McCarty C., Mirel D., Moroi S.E., Musch D.C., Realini A., Rozsa F.W., Schuman J.S., Scott K., Singh K., Stein J.D., Trager E.H., VanVeldhuisen P., Vollrath D., Wollstein G., Yoneyama S., Zhang K., Weinreb R.N., Ernst J., Kellis M., Masuda T., Zack D., Richards J.E., Pericak-Vance M., Pasquale L.R., Haines J.L.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2019
Subjects:	animal experiment animal model animal tissue article CDKN2BAS gene chromosome 14q chromosome 8q chromosome 9p controlled study disease association disease classification DNA sequence exfoliation syndrome gene gene expression profiling gene function gene location gene locus genetic association genetic identification genetic susceptibility genetic variability human intraocular pressure LRP12 gene major clinical study mouse nerve degeneration nonhuman open angle glaucoma optic nerve disease signal transduction single nucleotide polymorphism ZFPM2 gene allele chromosome 8 chromosome 9 genetics meta analysis metabolism optic nerve pathology ANRIL long non coding RNA, human ANRIL long non-coding RNA, human homeodomain protein SIX1 protein, human transforming growth factor beta untranslated RNA Alleles Chromosomes, Human, Pair 8 Chromosomes, Human, Pair 9 Exfoliation Syndrome Genome-Wide Association Study Glaucoma, Open-Angle Homeodomain Proteins Humans Nerve Degeneration Optic Nerve Polymorphism, Single Nucleotide RNA, Untranslated Transforming Growth Factor beta
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161641
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Institution:	National University of Singapore

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