The Janus-faced Nature of miR-22 in Hematopoiesis: Is It an Oncogenic Tumor Suppressor or Rather a Tumor-Suppressive Oncogene?

The Janus-faced Nature of miR-22 in Hematopoiesis: Is It an Oncogenic Tumor Suppressor or Rather a Tumor-Suppressive Oncogene?

10.1371/journal.pgen.1006505

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Bibliographic Details
Main Authors:	Wurm A.A., Tenen D.G., Behre G.
Other Authors:	MEDICINE
Format:	Article
Published:	2019
Subjects:	CCAAT enhancer binding protein alpha Janus kinase microRNA microRNA 181 microRNA 22 mixed lineage leukemia protein transcription factor PU 1 unclassified drug MIRN22 microRNA, human acute myeloid leukemia Article cell differentiation cell lineage gene expression hematopoiesis human leukemogenesis malignant transformation monocyte myelodysplastic syndrome myelopoiesis nonhuman oncogene macrophage tumor suppressor gene Genes, Tumor Suppressor Hematopoiesis Humans Leukemia, Myeloid, Acute Macrophages MicroRNAs Monocytes
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161901
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Institution:	National University of Singapore

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Summary:	10.1371/journal.pgen.1006505