Unique epitopes recognized by antibodies induced in chikungunya virus-infected non-human primates: Implications for the study of immunopathology and vaccine development

• Main Authors: Kam Y.-W., Lee W.W.L., Simarmata D., Le Grand R., Tolou H., Merits A., Roques P., Ng L.F.P.
• Other Authors: BIOCHEMISTRY
• Format: Article
• Published: Public Library of Science 2020
• Subjects: epitope; glycoprotein; neutralizing antibody; NSP1 protein; nsP3 protein; nsP4 protein; unclassified drug; virus protein; virus vaccine; immunoglobulin G; protein binding; virus antibody; virus antigen; animal experiment; animal model; antibody production; antibody response; antibody specificity; antigen recognition; article; chikungunya; Chikungunya alphavirus; controlled study; drug efficacy; enzyme linked immunosorbent assay; immune response; immunoblotting; immunopathology; kinetics; Macaca; nonhuman; virus capsid; animal; cell line; chemical structure; chemistry; Chikungunya Fever; disease model; epitope mapping; human; immunology; metabolism; primate; protein conformation; serodiagnosis; Animals; Antibodies, Neutralizing; Antibodies, Viral; Antibody Specificity; Antigens, Viral; Cell Line; Chikungunya virus; Disease Models, Animal; Epitope Mapping; Epitopes; Epitopes, B-Lymphocyte; Humans; Immunoglobulin G; Models, Molecular; Neutralization Tests; Primates; Protein Binding; Protein Conformation; Viral Proteins; Viral Vaccines
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165953
• Institution: National University of Singapore

10.1371/journal.pone.0095647