Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane X receptor

10.1124/dmd.111.042879

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Main Authors:	Lau, A.J, Yang, G, Rajaraman, G, Baucom, C.C, Chang, T.K.H
Other Authors:	PHARMACY
Format:	Article
Published:	American Society for Pharmacology and Experimental Therapeutics 2020
Subjects:	16alpha cyanopregnenolone bilobalide constitutive androstane receptor cytochrome P450 2B cytochrome P450 2B1 cytochrome P450 2B6 cytochrome P450 3A cytochrome P450 3A23 cytochrome P450 3A4 messenger RNA pregnane X receptor rifampicin unclassified drug animal cell article concentration response controlled study drug mechanism enzyme activation enzyme activity gene expression gene location gene targeting human human cell hydroxylation liver cell nonhuman nucleotide sequence priority journal protein function protein localization protein targeting rat reporter gene Animals Cell Line, Tumor Cells, Cultured Cyclopentanes Furans Ginkgolides Hep G2 Cells Hepatocytes Humans Rats Receptors, Cytoplasmic and Nuclear Receptors, Steroid Species Specificity
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/183910
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-183910
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spelling	sg-nus-scholar.10635-1839102024-04-05T09:02:21Z Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane X receptor Lau, A.J Yang, G Rajaraman, G Baucom, C.C Chang, T.K.H PHARMACY 16alpha cyanopregnenolone bilobalide constitutive androstane receptor cytochrome P450 2B cytochrome P450 2B1 cytochrome P450 2B6 cytochrome P450 3A cytochrome P450 3A23 cytochrome P450 3A4 messenger RNA pregnane X receptor rifampicin unclassified drug animal cell article concentration response controlled study drug mechanism enzyme activation enzyme activity gene expression gene location gene targeting human human cell hydroxylation liver cell nonhuman nucleotide sequence priority journal protein function protein localization protein targeting rat reporter gene Animals Cell Line, Tumor Cells, Cultured Cyclopentanes Furans Ginkgolides Hep G2 Cells Hepatocytes Humans Rats Receptors, Cytoplasmic and Nuclear Receptors, Steroid Species Specificity 10.1124/dmd.111.042879 Drug Metabolism and Disposition 40 1 178-186 2020-11-23T08:59:43Z 2020-11-23T08:59:43Z 2012 Article Lau, A.J, Yang, G, Rajaraman, G, Baucom, C.C, Chang, T.K.H (2012). Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane X receptor. Drug Metabolism and Disposition 40 (1) : 178-186. ScholarBank@NUS Repository. https://doi.org/10.1124/dmd.111.042879 0090-9556 https://scholarbank.nus.edu.sg/handle/10635/183910 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ American Society for Pharmacology and Experimental Therapeutics Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	16alpha cyanopregnenolone bilobalide constitutive androstane receptor cytochrome P450 2B cytochrome P450 2B1 cytochrome P450 2B6 cytochrome P450 3A cytochrome P450 3A23 cytochrome P450 3A4 messenger RNA pregnane X receptor rifampicin unclassified drug animal cell article concentration response controlled study drug mechanism enzyme activation enzyme activity gene expression gene location gene targeting human human cell hydroxylation liver cell nonhuman nucleotide sequence priority journal protein function protein localization protein targeting rat reporter gene Animals Cell Line, Tumor Cells, Cultured Cyclopentanes Furans Ginkgolides Hep G2 Cells Hepatocytes Humans Rats Receptors, Cytoplasmic and Nuclear Receptors, Steroid Species Specificity
spellingShingle	16alpha cyanopregnenolone bilobalide constitutive androstane receptor cytochrome P450 2B cytochrome P450 2B1 cytochrome P450 2B6 cytochrome P450 3A cytochrome P450 3A23 cytochrome P450 3A4 messenger RNA pregnane X receptor rifampicin unclassified drug animal cell article concentration response controlled study drug mechanism enzyme activation enzyme activity gene expression gene location gene targeting human human cell hydroxylation liver cell nonhuman nucleotide sequence priority journal protein function protein localization protein targeting rat reporter gene Animals Cell Line, Tumor Cells, Cultured Cyclopentanes Furans Ginkgolides Hep G2 Cells Hepatocytes Humans Rats Receptors, Cytoplasmic and Nuclear Receptors, Steroid Species Specificity Lau, A.J Yang, G Rajaraman, G Baucom, C.C Chang, T.K.H Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane X receptor
description	10.1124/dmd.111.042879
author2	PHARMACY
author_facet	PHARMACY Lau, A.J Yang, G Rajaraman, G Baucom, C.C Chang, T.K.H
format	Article
author	Lau, A.J Yang, G Rajaraman, G Baucom, C.C Chang, T.K.H
author_sort	Lau, A.J
title	Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane X receptor
title_short	Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane X receptor
title_full	Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane X receptor
title_fullStr	Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane X receptor
title_full_unstemmed	Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane X receptor
title_sort	species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane x receptor
publisher	American Society for Pharmacology and Experimental Therapeutics
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/183910
_version_	1800914732095373312

Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane X receptor

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