TARGETING P53 DEFICIENCY IN CANCER THROUGH SYNTHETIC LETHALITY

TARGETING P53 DEFICIENCY IN CANCER THROUGH SYNTHETIC LETHALITY

Ph.D

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	GAMAL AHMED RASHED ELSAYED ELFAR
مؤلفون آخرون:	DEAN'S OFFICE (MEDICINE)
التنسيق:	Theses and Dissertations
اللغة:	English
منشور في:	2024
الموضوعات:	p53, ATRi, RRM2B, oxidative stress, PARylation, replication stress
الوصول للمادة أونلاين:	https://scholarbank.nus.edu.sg/handle/10635/247098
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة

THE ROLE OF P53 IN S PHASE AND IN DEALING WITH REPLICATION STRESS
بواسطة: OBED AKWASI ANING
منشور في: (2019)

Exploiting cancer's antioxidative weakness through p53 with nanotoxicology
بواسطة: Setyawati, M.I., وآخرون
منشور في: (2014)

THE ROLE OF P53 IN MAINTAINING GENOME STABILITY
بواسطة: NGAI TSZ WAI
منشور في: (2021)

P53 protects lung cancer cells against metabolic stress
بواسطة: Chompunoot Sinthupibulyait, وآخرون
منشور في: (2013)

Serine 312 phosphorylation is dispensable for wild-type p53 functions in vivo
بواسطة: Lee, M.K., وآخرون
منشور في: (2014)

Sirt1 antagonizes Stra13 Mediated p53 Acetylation and Senescence
بواسطة: TAN YONG HUA
منشور في: (2014)

Sharp-1 Mediates p53 - dependent cellular senescence through antagonism of Sirt1
بواسطة: JOCELYN JIN YU
منشور في: (2014)

DECIPHERING THE MOLECULAR DYNAMICS INVOLVED IN THE INDUCTION OF SENESCENCE IN CELLS EXPOSED TO SUBTOXIC LEVELS OF OXIDATIVE STRESS
بواسطة: GIREEDHAR VENKATACHALAM
منشور في: (2015)

Drugging in the absence of p53
بواسطة: Aning, Obed Akwasi, وآخرون
منشور في: (2021)

Ectopic mTERT expression in mouse embryonic stem cells does not affect differentiation but confers resistance to differentiation- and stress-induced p53-dependent apoptosis
بواسطة: Lee, M.K., وآخرون
منشور في: (2014)

Induction of p53 Renders ATM-Deficient Mice Refractory to Hepatocarcinogenesis
بواسطة: Teoh, N., وآخرون
منشور في: (2011)

GENOMIC AND FUNCTIONAL CHARACTERIZATION OF THE P53 PATHWAY IN RELATION TO 17P13 (DEL) IN MULTIPLE MYELOMA
بواسطة: TEOH PHAIK JU
منشور في: (2015)

Expression of nitric oxide synthase, cyclooxygenase, and p53 in different stages of human gastric cancer
بواسطة: Rajnakova, A., وآخرون
منشور في: (2014)

CHARACTERIZATION OF P53-MEDIATED TRANSCRIPTION DEREGULATION BY THE HEPATITIS B VIRUS X PROTEIN
بواسطة: CHAN SIEW CHOO CHERYL
منشور في: (2012)

Targeting p53 as a therapeutic strategy in sensitizing TRAIL-induced apoptosis in cancer cells
بواسطة: Zhao, J., وآخرون
منشور في: (2014)

Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress
بواسطة: Venkatachalam, G, وآخرون
منشور في: (2022)

Roles of computational modelling in understanding p53 structure, biology, and its therapeutic targeting
بواسطة: Tan, Yaw Sing, وآخرون
منشور في: (2019)

The anti-oxidant defense system of the marine polar ciliate euplotes nobilii : characterization of the msrb gene family
بواسطة: Ricci, Francesca, وآخرون
منشور في: (2018)

Cyr61/CCN1 is a tumor suppressor in human hepatocellular carcinoma and involved in DNA damage response
بواسطة: Feng, P., وآخرون
منشور في: (2011)

Aflatoxin-B exposure does not lead to p53 mutations but results in enhanced liver cancer of Hupki (human p53 knock-in) mice
بواسطة: Tong, W.-M., وآخرون
منشور في: (2014)

Effect of zinc oxide nanomaterials-induced oxidative stress on the p53 pathway
بواسطة: Setyawati, M.I., وآخرون
منشور في: (2014)

Roles of computational modelling in understanding p53 structure, biology, and its therapeutic targeting
بواسطة: Tan, Y.S., وآخرون
منشور في: (2021)

The role of the tumor suppressor p53 pathway in the cellular DNA damage response to zinc oxide nanoparticles
بواسطة: Ng, K.W., وآخرون
منشور في: (2014)

The role of the tumor suppressor p53 pathway in the cellular DNA damage response to zinc oxide nanoparticles
بواسطة: Ng, K.W., وآخرون
منشور في: (2014)

Mutations of the p53 tumor suppressor gene and ras oncogenes in aflatoxin hepatocarcinogenesis
بواسطة: Shen, H.-M., وآخرون
منشور في: (2014)

NF-?B-MEDIATED INTEGRIN ?3 EXPRESSION LEADS TO INCREASED LAMELLIPODIA FORMATION AND STAT3 ACTIVITY IN p53-DEPLETED CELLS
بواسطة: GUO KUNYAO, ALVIN
منشور في: (2014)

Functional study of zebrafish Udu and its relationship to the Notch signaling pathway
بواسطة: LIM CHIAW HWEE
منشور في: (2011)

Role of nitric oxide in cancer biology
بواسطة: Moochhala, S., وآخرون
منشور في: (2016)

Recombinant adenovirus-p53 (Gendicine) sensitizes a pancreatic carcinoma cell line to radiation
بواسطة: Li, J., وآخرون
منشور في: (2016)

Role of a Burkholderia pseudomallei polyphosphate kinase in an oxidative stress response, motilities, and biofilm formation
بواسطة: Suda Tunpiboonsak, وآخرون
منشور في: (2015)

An immunohistochemical study of p53 protein in ovarian mucinous neoplasms
بواسطة: Teh, M., وآخرون
منشور في: (2012)

The study of oxidative stress response in Xanthomonas spp.
بواسطة: Paiboon Vattanaviboon
منشور في: (2023)

Therapeutic potential of antisense oligodeoxynucleotides in downregulating p53 oncogenic mutations in cancers
بواسطة: Xie, Z., وآخرون
منشور في: (2014)

Understanding p53 functions through p53 antibodies
بواسطة: Sabapathy, K., وآخرون
منشور في: (2021)

PATZ1 (MAZR) Co-occupies Genomic Sites With p53 and Inhibits Liver Cancer Cell Proliferation via Regulating p27
بواسطة: Ng, Zhen Long, وآخرون
منشور في: (2022)

Antioxidants: Promising neuroprotection against cardiotoxin-4b-induced cell death which triggers oxidative stress with early calpain activation
بواسطة: Toh, T.B., وآخرون
منشور في: (2011)

Association study of p53 codon 72 polymorphism in Parkinson's disease
بواسطة: Siddique, M.M., وآخرون
منشور في: (2016)

In silico and molecular docking analysis of the flavones present in colocasia esculenta (L.) schott with the 1tsr p53 Protein
بواسطة: Tacderas, Mary Teresa Beatrice B., وآخرون
منشور في: (2022)

P53-related transcription targets of TAp73 in cancer cells—bona fide or distorted reality?
بواسطة: Wang, C., وآخرون
منشور في: (2021)

Antimalarial activity of artemisinin : an iron-dependent mechanism of action
بواسطة: Nathawut Sibmooh
منشور في: (2023)