Tabernaemontana divaricata extract inhibits neuronal acetylcholinesterase activity in rats

• المؤلفون الرئيسيون: Chattipakorn S., Pongpanparadorn A., Pratchayasakul W., Pongchaidacha A., Ingkaninan K., Chattipakorn N.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?eid=2-s2.0-33846827338&partnerID=40&md5=f9a2a402021268e6e20a21dcfa78345b; http://www.ncbi.nlm.nih.gov/pubmed/17023131; http://cmuir.cmu.ac.th/handle/6653943832/1018

The current pharmacotherapy for Alzheimer's disease (AD) is the use of acetylcholinesterase inhibitors (AChE-Is). A previous in vitro study showed that Tabernaemontana divaricata extract (TDE) can inhibit AChE activity. However, neither the AChE inhibitory effects nor the effect on neuronal act...