Anemia and hydrops in a fetus with homozygous hemoglobin constant spring

• Main Authors: Charoenkwan P., Sirichotiyakul S., Chanprapaph P., Tongprasert F., Taweephol R., Sae-Tung R., Sanguansermsri T.
• 格式: Article
• 語言: English
• 出版: 2014
• 在線閱讀: http://www.scopus.com/inward/record.url?eid=2-s2.0-33845686816&partnerID=40&md5=50ebd4cef02d134adcac5c50054b50ab; http://www.ncbi.nlm.nih.gov/pubmed/17164653; http://cmuir.cmu.ac.th/handle/6653943832/1985
• 機構: Chiang Mai University

Hemoglobin Constant Spring (Hb CS) is an unstable hemoglobin (Hb) variant that results from a nucleotide substitution at the termination codon of the α2-globin gene. The compound heterozygosity of α-thalassemia and Hb CS (-/αα) results in a Hb H/CS disease which is clinically more severe than deleti...