Generation of functional scFv intrabody to abate the expression of CD147 surface molecule of 293A cells

• المؤلفون الرئيسيون: Tragoolpua K., Intasai N., Kasinrerk W., Mai S., Yuan Y., Tayapiwatana C.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?eid=2-s2.0-39849084770&partnerID=40&md5=14a0e841282b882c246689f265927573; http://www.ncbi.nlm.nih.gov/pubmed/18226275; http://cmuir.cmu.ac.th/handle/6653943832/2494
• المؤسسة: Chiang Mai University

Background: Expression of intracellular antibodies (intrabodies) has become a broadly applicable technology for generation of phenotypic knockouts in vivo. The method uses surface depletion of cellular membrane proteins to examine their biological function. In this study, we used this strategy to bl...