Renal and metabolic toxicities following initiation of HIV-1 treatment regimen in a diverse, multinational setting: A focused safety analysis of ACTG PEARLS (A5175)

• Main Authors: Touzard Romo,F., Smeaton,L.M., Campbell,T.B., Rivière,C., Mngqibisa,R., Nyirenda,M.J., Supparatpinyo,K., Kumarasamy,N., Hakim,J.G., Flanigan,T.P.
• 格式: Article
• 出版: Thomas Land Publishers Inc. 2015
• 主題: Pharmacology (medical); Infectious Diseases
• 在線閱讀: http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84916201328&origin=inward; http://cmuir.cmu.ac.th/handle/6653943832/38347

© 2014 Thomas Land Publishers, Inc. Background: Convenient dosing, potency, and low toxicity support use of tenofovir disoproxil fumarate (TDF) as preferred nucleotide reverse transcriptase inhibitor (NRTI) for HIV-1 treatment. However, renal and metabolic safety of TDF compared to other NRTIs has n...