MS analysis of single-nucleotide differences in circulating nucleic acids: Application to noninvasive prenatal diagnosis

• المؤلفون الرئيسيون: Ding C., Chiu R.W.K., Lau T.K., Leung T.N., Chan L.C., Chan A.Y.Y., Charoenkwan P., Ng I.S.L., Law H.-Y., Ma E.S.K., Xu X., Wanapirak C., Sanguansermsri T., Liao C., Tan Jin Ai M.A., Chui D.H.K., Cantor C.R., Lo Y.M.D.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?eid=2-s2.0-3242703837&partnerID=40&md5=1682349cfcbd800a0fbe16b7bb84f251; http://cmuir.cmu.ac.th/handle/6653943832/3982

The analysis of circulating nucleic acids has revealed applications in the noninvasive diagnosis, monitoring, and prognostication of many clinical conditions. Circulating fetal-specific sequences have been detected and constitute a fraction of the total DNA in maternal plasma. The diagnostic reliabi...