Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles

© 2016 Elsevier Ltd A sonochemical method for the synthesis of 2-aminobenzimidazoles and 2-aminobenzoxazoles, as well as chiral aminooxazolines and a chiral substituted quinazolin-5-one is reported. Using the Ph 3 P–I 2 system in the presence of triethylamine as a desulfurization agent, monothiourea...

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Main Authors: Phakhodee W., Duangkamol C., Wiriya N., Pattarawarapan M.
Format: Journal
Published: 2017
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84994322327&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/42233
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-422332017-09-28T04:25:58Z Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles Phakhodee W. Duangkamol C. Wiriya N. Pattarawarapan M. © 2016 Elsevier Ltd A sonochemical method for the synthesis of 2-aminobenzimidazoles and 2-aminobenzoxazoles, as well as chiral aminooxazolines and a chiral substituted quinazolin-5-one is reported. Using the Ph 3 P–I 2 system in the presence of triethylamine as a desulfurization agent, monothioureas prepared in situ from the reaction of bis-nucleophiles with isothiocyanates underwent rapid cyclization to afford a variety of N-heterocyclic compounds in good to excellent yields under mild conditions. 2017-09-28T04:25:58Z 2017-09-28T04:25:58Z 2016-01-01 Journal 00404039 2-s2.0-84994322327 10.1016/j.tetlet.2016.10.060 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84994322327&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/42233
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
description © 2016 Elsevier Ltd A sonochemical method for the synthesis of 2-aminobenzimidazoles and 2-aminobenzoxazoles, as well as chiral aminooxazolines and a chiral substituted quinazolin-5-one is reported. Using the Ph 3 P–I 2 system in the presence of triethylamine as a desulfurization agent, monothioureas prepared in situ from the reaction of bis-nucleophiles with isothiocyanates underwent rapid cyclization to afford a variety of N-heterocyclic compounds in good to excellent yields under mild conditions.
format Journal
author Phakhodee W.
Duangkamol C.
Wiriya N.
Pattarawarapan M.
spellingShingle Phakhodee W.
Duangkamol C.
Wiriya N.
Pattarawarapan M.
Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
author_facet Phakhodee W.
Duangkamol C.
Wiriya N.
Pattarawarapan M.
author_sort Phakhodee W.
title Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
title_short Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
title_full Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
title_fullStr Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
title_full_unstemmed Ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
title_sort ultrasound-assisted synthesis of substituted 2-aminobenzimidazoles, 2-aminobenzoxazoles, and related heterocycles
publishDate 2017
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84994322327&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/42233
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