Enhanced doxorubicin delivery and cytotoxicity in multidrug resistant cancer cells using multifunctional magnetic nanoparticles

• المؤلفون الرئيسيون: Chalermchai Pilapong, Yanee Keereeta, Samlee Munkhetkorn, Somchai Thongtem, Titipun Thongtem
• التنسيق: دورية
• منشور في: 2018
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84885049849&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/45422
• المؤسسة: Chiang Mai University

Carboxymethyl modified magnetic nanoparticles (CMC-MNPs) have been designed as a vehicle for drug delivery in both drug-sensitive and drug-resistant cancer cells. We have demonstrated that the CMC-MNPs were able to load doxorubicin (DOX) with a high loading efficiency while also maintaining a good c...