Growth Hormone (GH)-dependent expression of a natural antisense transcript induces zinc finger E-box-binding homeobox 2 (ZEB2) in the glomerular podocyte: A novel action of GH with implications for the pathogenesis of diabetic nephropathy

• المؤلفون الرئيسيون: P. Anil Kumar, Kateryna Kotlyarevska, Prapai Dejkhmaron, Gaddameedi R. Reddy, Chunxia Lu, Mahaveer S. Bhojani, Ram K. Menon
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Medicine
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77957759709&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/50531
• المؤسسة: Chiang Mai University

Growth hormone (GH) excess results in structural and functional changes in the kidney and is implicated as a causative factor in the development of diabetic nephropathy (DN). Glomerular podocytes are the major barrier to the filtration of serum proteins, and altered podocyte function and/or reduced...