Growth Hormone (GH)-dependent expression of a natural antisense transcript induces zinc finger E-box-binding homeobox 2 (ZEB2) in the glomerular podocyte: A novel action of GH with implications for the pathogenesis of diabetic nephropathy

• Main Authors: P. Anil Kumar, Kateryna Kotlyarevska, Prapai Dejkhmaron, Gaddameedi R. Reddy, Chunxia Lu, Mahaveer S. Bhojani, Ram K. Menon
• 格式: 雜誌
• 出版: 2018
• 主題: Biochemistry, Genetics and Molecular Biology; Medicine
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77957759709&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/50531

Growth hormone (GH) excess results in structural and functional changes in the kidney and is implicated as a causative factor in the development of diabetic nephropathy (DN). Glomerular podocytes are the major barrier to the filtration of serum proteins, and altered podocyte function and/or reduced...