Albumin-conjugated pH/Thermo responsive poly(amino urethane) multiblock copolymer as an injectable hydrogel for protein delivery

• Main Authors: Kiattikhun Manokruang, Doo Sung Lee
• 格式: 雜誌
• 出版: 2018
• 主題: Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Materials Science
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84884816623&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/52211

Albumin-conjugated pH and thermo responsive poly(amino urethane) multiblock copolymers are synthesized. The aqueous solution of the conjugate exhibits pH/temperature dependent sol-gel phase transitions that can be tuned by changing solution concentration and albumin composition. The gel window well...