Anti-inflammatory activity of 4-arylcoumarins from endophytic Streptomyces aureofaciens CMUAc130 in murine macrophage RAW 264.7 cells

• Main Authors: Taechowisan T., Tuntiwachwuttikul P., Lu C., Shen Y., Lumyong S., Taylor W.C.
• 格式: Article
• 語言: English
• 出版: 2014
• 在線閱讀: http://www.scopus.com/inward/record.url?eid=2-s2.0-33847747111&partnerID=40&md5=10194048b1d2d3c86aeb9ff99955a439; http://cmuir.cmu.ac.th/handle/6653943832/5298
• 機構: Chiang Mai University

This research was undertaken to test the in vitro anti-inflammatory action of 5,7,4′-trimethoxy-4-phenylcoumarin and 5,7-dimethoxy-4-phenylcoumarin produced by Streptomyces aureofaciens CMUAc130. The effects of the two coumarins were investigated on the formation of NO, PGE2, and TNF-α and also on i...