Current development on HIV-1 protease inhibitors

• Main Authors: Ornjira Arusksakunwong, Siriporn Promsri, Kitiyaporn Wittayanarakul, Piyarat Nimmanpipug, Vannajan S. Lee, Atchara Wijitkosoom, Pornthep Sompornpisut, Supot Hannongbua
• 格式: 雜誌
• 出版: 2018
• 主題: Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=51949109972&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/60868

Although a number of potent and selective inhibitors have been developed and approved as drugs for the treatment of HIV infection, efforts still needed in order to develop new inhibitors that are more potent, have unique resistance patterns, and minimal side effects. This review focuses to the HIV-1...