Exchange protein activated by cyclic-adenosine monophosphate (Epac) regulates atrial fibroblast function and controls cardiac remodelling

• المؤلفون الرئيسيون: Sirirat Surinkaew, Mona Aflaki, Abhijit Takawale, Yu Chen, Xiao Yan Qi, Marc Antoine Gillis, Yan Fen Shi, Jean Claude Tardif, Nipon Chattipakorn, Stanley Nattel
• التنسيق: دورية
• منشور في: 2019
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Medicine
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85058921719&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/63589

© The Author(s) 2018. Aims Heart failure (HF) produces left atrial (LA)-selective fibrosis and promotes atrial fibrillation. HF also causes adrenergic activation, which contributes to remodelling via a variety of signalling molecules, including the exchange protein activated by cAMP (Epac). Here, we...