Pharmacokinetics of oral tenofovir disoproxil fumarate in pregnancy and lactation: a systematic review

• Main Authors: Marieke Bierhoff, Elise J. Smolders, Joel Tarning, David M. Burger, Rene Spijker, Marcus J. Rijken, Chaisiri Angkurawaranon, Rose McGready, Nicholas J. White, Francois Nosten, Michèle van Vugt
• 格式: 雜誌
• 出版: 2020
• 主題: Medicine; Pharmacology, Toxicology and Pharmaceutics
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85079203745&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/68022
• 機構: Chiang Mai University

BACKGROUND: Tenofovir disoproxil fumarate (TDF), the oral prodrug of tenofovir (TFV), is advocated in pregnancy for prevention of mother-to-child transmission (PMCT) with failure of hepatitis B immunoglobulin and vaccination. The pharmacokinetics of TDF monotherapy for PMCT-HBV is important if deplo...