Production of monoclonal antibody to CD4 antigen and development of reagent for CD4+ lymphocyte enumeration

• المؤلفون الرئيسيون: Kasinrerk W., Tokrasinwit N., Naveewongpanit P.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.ncbi.nlm.nih.gov/pubmed/3502482; http://cmuir.cmu.ac.th/handle/6653943832/827
• المؤسسة: Chiang Mai University

A hybridoma secreting monoclonal antibody (mAb) specific to CD4 protein was generated. This monoclonal antibody, named MT4, was proved to be specific to CD4 protein as it reacted with CD4-DNA transfected COS cells, CD4+ cell lines and CD4+ lymphocytes. Furthermore, MT4 mAb inhibited the binding of s...