Potential of edaravone for neuroprotection in neurologic diseases that do not involve cerebral infarction (Review)

• Main Authors: Kiyoshi Kikuchi, Ko Ichi Kawahara, Hisaaki Uchikado, Naohisa Miyagi, Terukazu Kuramoto, Tomoya Miyagi, Yoko Morimoto, Takashi Ito, Salunya Tancharoen, Naoki Miura, Kazunori Takenouchi, Yoko Oyama, Binita Shrestha, Fumiyo Matsuda, Yoshihiro Yoshida, Shinihiro Arimura, Kentaro Mera, Ko Ichi Tada, Narimasa Yoshinaga, Ryuichi Maenosono, Yoshiko Ohno, Teruto Hashiguchi, Ikuro Maruyama, Minoru Shigemori
• Other Authors: Yame General Hospital
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/11482
• Institution: Mahidol University

Edaravone was originally developed as a potent free radical scavenger and has been widely used to treat cerebral infarction in Japan since 2001. Several free radical scavengers have been developed and some of them have progressed to clinical trials for the treatment of cerebral infarction. One such...