Liquid chromatographic-mass spectrometric method for simultaneous determination of small organic acids potentially contributing to acidosis in severe malaria

Acidosis is an important cause of mortality in severe falciparum malaria. Lactic acid is a major contributor to metabolic acidosis, but accounts for only one-quarter of the strong anion gap. Other unidentified organic acids have an independent strong prognostic significance for a fatal outcome. In t...

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Bibliographic Details
Main Authors: Natthida Sriboonvorakul, Natchanun Leepipatpiboon, Arjen M. Dondorp, Thomas Pouplin, Nicholas J. White, Joel Tarning, Niklas Lindegardh
Other Authors: Chulalongkorn University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/31140
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Institution: Mahidol University