Cell-type-specific transcriptional profiles of the dimorphic pathogen penicillium marneffei reflect distinct reproductive, morphological, and environmental demands

• Main Authors: Shivani Pasricha, Michael Payne, David Canovas, Luke Pase, Nathamon Ngaosuwankul, Sally Beard, Alicia Oshlack, Gordon K. Smyth, Sansanee C. Chaiyaroj, Kylie J. Boyce, Alex Andrianopoulos
• 其他作者: University of Melbourne
• 格式: Article
• 出版: 2018
• 主題: Biochemistry, Genetics and Molecular Biology; Medicine
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/31423
• 機構: Mahidol University

Penicillium marneffei is an opportunistic human pathogen endemic to Southeast Asia. At 25° P. marneffei grows in a filamentous hyphal form and can undergo asexual development (conidiation) to produce spores (conidia), the infectious agent. At 37° P. marneffei grows in the pathogenic yeast cell form...