Validation of a chloroquine-induced cell death mechanism for clinical use against malaria

Validation of a chloroquine-induced cell death mechanism for clinical use against malaria

An alternative antimalarial pathway of an 'outdated' drug, chloroquine (CQ), may facilitate its return to the shrinking list of effective antimalarials. Conventionally, CQ is believed to interfere with hemozoin formation at nanomolar concentrations, but resistant parasites are able to effl...

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Bibliographic Details
Main Authors: J. H. Ch'ng, Y. Q. Lee, S. Y. Gun, W. N. Chia, Z. W. Chang, L. K. Wong, K. T. Batty, B. Russell, F. Nosten, L. Renia, K. S.W. Tan
Other Authors: National University of Singapore
Format: Article
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Immunology and Microbiology
Neuroscience
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/33514
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/33514

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