Isolated CyaA-RTX subdomain from Bordetella pertussis: Structural and functional implications for its interaction with target erythrocyte membranes

• المؤلفون الرئيسيون: Riyaz Ahmad Pandit, Kanungsuk Meetum, Kittipong Suvarnapunya, Gerd Katzenmeier, Wanpen Chaicumpa, Chanan Angsuthanasombat
• مؤلفون آخرون: Mahidol University
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/35394

© 2015 Elsevier Inc. The 126-kDa Bordetella pertussis CyaA-hemolysin (CyaA-Hly) was previously expressed in Escherichia coli as a soluble precursor that can be acylated to retain hemolytic activity. Here, we investigated structural and functional characteristics of a ∼100-kDa isolated RTX (Repeat-in...