Novel subcutaneous low-molecular-weight heparin injection technique to reduce post-injection bruising

© The Author(s) 2018. Objective: To investigate the efficacy of a novel low-molecular-weight heparin injection technique compared to the standard technique relative to bruising incidence, bruise size, and pain. Methods: A randomized controlled trial was conducted in 44 patients with acute deep vein...

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Bibliographic Details
Main Authors: Sommapun Jueakaew, Rattana Piancharoensin, Natchayakorn Pinkesorn, Sarunya Thippayarom, Nuttawut Sermsathanasawadi
Other Authors: Faculty of Medicine, Siriraj Hospital, Mahidol University
Format: Article
Published: 2020
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/51553
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Institution: Mahidol University
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Summary:© The Author(s) 2018. Objective: To investigate the efficacy of a novel low-molecular-weight heparin injection technique compared to the standard technique relative to bruising incidence, bruise size, and pain. Methods: A randomized controlled trial was conducted in 44 patients with acute deep vein thrombosis. Patients who were randomized into the control group received a 10-s duration injection with immediate needle withdrawal, whereas study group patients received a 30-s duration injection with a 10-s pause before needle withdrawal. Two injection sites were assessed for pain and bruising between 48 and 60 h after injection. Results: Bruises occurred in 50.0% and 18.2% of control and study group patients, respectively (p = 0.03). Mean bruise size between 48 and 60 h after injection was 172.73 ± 372.60 mm2 and 28.18 ± 70.01 mm2 in the control group and study group, respectively (p = 0.026). Pain scores were comparable between groups. Conclusion: A 30-s duration injection with a 10-s pause before needle withdrawal resulted in significantly fewer and smaller bruises.