Disparities in Dolutegravir Uptake Affecting Females of Reproductive Age With HIV in Low- and Middle-Income Countries After Initial Concerns About Teratogenicity An Observational Study

• Main Authors: Matthew L. Romo, Rena C. Patel, Jessie K. Edwards, John M. Humphrey, Beverly S. Musick, Caitlin Bernard, Mercy W. Maina, Ellen Brazier, Barbara Castelnuovo, Jeremy Penner, Katarzyna Wyka, Sandra Wagner Cardoso, Penh Sun Ly, Cordelia Kunzekwenyika, Claudia P. Cortés, Radoslaw Panczak, Elizabeth A. Kelvin, Kara K. Wools-Kaloustian, Denis Nash, V. Khol, F. J. Zhang, H. X. Zhao, N. Han, M. P. Lee, P. C.K. Li, W. Lam, H. Y. Wong, N. Kumarasamy, C. Ezhilarasi, S. Pujari, K. Joshi, S. Gaikwad, A. Chitalikar, T. P. Merati, D. N. Wirawan, F. Yuliana, E. Yunihastuti, D. Imran, A. Widhani, J. Tanuma, S. Oka, T. Nishijima, J. Y. Choi, S. Na, J. M. Kim, Y. M. Gani, N. B. Rudi, I. Azwa, A. Kamarulzaman, S. F. Syed Omar, S. Ponnampalavanar, R. Ditangco, M. K. Pasayan, M. L. Mationg, Y. J. Chan, W. W. Ku, E. Ke, P. C. Wu, O. T. Ng, P. L. Lim, L. S. Lee, J. K. Yap, A. Avihingsanon, S. Gatechompol, P. Phanuphak, C. Phadungphon, S. Kiertiburanakul, A. Phuphuakrat, L. Chumla, N. Sanmeema, R. Chaiwarith, T. Sirisanthana, J. Praparattanapan, K. Nuket, S. Khuwuwan, P. Kantipong, P. Kambua, K. V. Nguyen, H. V. Bui, D. T.H. Nguyen, D. T. Nguyen, C. D. Do, A. V. Ngo, L. T. Nguyen, A. H. Sohn, J. L. Ross, B. Petersen, M. G. Law, A. Jiamsakul, R. Bijker, D. Rupasinghe, Pedro Cahn, Carina Cesar, Valeria Fink, Omar Sued, Emanuel Dell'Isola, Hector Perez, Jose Valiente, Cleyton Yamamoto, Beatriz Grinsztejn
• Other Authors: Makerere University College of Health Sciences
• Format: Article
• Published: 2022
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/75100
• Institution: Mahidol University

Background: The transition to dolutegravir-containing antiretroviral therapy (ART) in low- and middle-income countries (LMICs) was complicated by an initial safety signal in May 2018 suggesting that exposure to dolutegravir at conception was possibly associated with infant neural tube defects. On th...