Chloroquine is grossly under dosed in young children with malaria: implications for drug resistance.

Chloroquine is grossly under dosed in young children with malaria: implications for drug resistance.

BACKGROUND: Plasmodium falciparum malaria is treated with 25 mg/kg of chloroquine (CQ) irrespective of age. Theoretically, CQ should be dosed according to body surface area (BSA). The effect of dosing CQ according to BSA has not been determined but doubling the dose per kg doubled the efficacy of CQ...

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Bibliographic Details
Main Authors: Ursing, Johan, Eksborg, Staffan, Rombo, Lars, Bergqvist, Yngve, Blessborn, Daniel, Rodrigues, Amabelia, Kofoed, Poul-Erik
Format: Article
Language:English
Published: 2014
Subjects:
Antimalarials
Chloroquine
Drug resistance
Malaria
Open Access article
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/753
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Institution: Mahidol University
Language: English

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https://repository.li.mahidol.ac.th/handle/123456789/753

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