Different mutant RUNX1 oncoproteins program alternate haematopoietic differentiation trajectories

بواسطة Kellaway, SG, Keane, P, Edginton-White, B, Regha, K, Kennett, E, Bonifer, C
منشور في 2022

Developmental-stage-dependent transcriptional response to leukaemic oncogene expression

بواسطة Regha, K, Assi, S.A, Tsoulaki, O, Gilmour, J, Lacaud, G, Bonifer, C
منشور في 2020

Early chromatin unfolding by RUNX1: A molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

بواسطة Hoogenkamp, M., Lichtinger, M., Krysinska, H., Clarke, D., Ingram, R., Bonifer, C., Lancrin, C., Lacaud, G., Williamson, A., Kouskoff, V., Mazzarella, L., Jorgensen, H., Fisher, A., Tenen, D.G.
منشور في 2011

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

بواسطة Leddin, M., Perrod, C., Hoogenkamp, M., Ghani, S., Assi, S., Heinz, S., Wilson, N.K., Follows, G., Schönheit, J., Vockentanz, L., Mosammam, A.M., Chen, W., Tenen, D.G., Westhead, D.R., Göttgens, B., Bonifer, C., Rosenbauer, F.
منشور في 2016

RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis

بواسطة Lichtinger, M., Ingram, R., Hannah, R., Müller, D., Clarke, D., Assi, S.A., Lie-A-Ling, M., Noailles, L., Vijayabaskar, M.S., Wu, M., Tenen, D.G., Westhead, D.R., Kouskoff, V., Lacaud, G., Göttgens, B., Bonifer, C.
منشور في 2016

RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element

بواسطة Levantini, E., Lee, S., Radomska, H.S., Hetherington, C.J., Alberich-Jorda, M., Amabile, G., Zhang, P., Gonzalez, D.A., Zhang, J., Basseres, D.S., Wilson, N.K., Koschmieder, S., Huang, G., Zhang, D.-E., Ebralidze, A.K., Bonifer, C., Okuno, Y., Gottgens, B., Tenen, D.G.
منشور في 2014

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding

بواسطة Ptasinska, A., Assi, S.A., Mannari, D., James, S.R., Williamson, D., Dunne, J., Hoogenkamp, M., Wu, M., Care, M., McNeill, H., Cauchy, P., Cullen, M., Tooze, R.M., Tenen, D.G., Young, B.D., Cockerill, P.N., Westhead, D.R., Heidenreich, O., Bonifer, C.
منشور في 2014

Sox4 Is a Key Oncogenic Target in C/EBPα Mutant Acute Myeloid Leukemia

بواسطة Zhang, H., Alberich-Jorda, M., Amabile, G., Yang, H., Staber, P.B., DiRuscio, A., Welner, R.S., Ebralidze, A., Zhang, J., Levantini, E., Lefebvre, V., Valk, P.J.M., Delwel, R., Hoogenkamp, M., Nerlov, C., Cammenga, J., Saez, B., Scadden, D.T., Bonifer, C., Ye, M., Tenen, D.G.
منشور في 2016