Innovative Approaches for Pharmacology Studies in Pregnant and Lactating Women: A Viewpoint and Lessons from HIV

by Ahizechukwu C. Eke, Adeniyi Olagunju, Brookie M. Best, Mark Mirochnick, Jeremiah D. Momper, Elaine Abrams, Martina Penazzato, Tim R. Cressey, Angela Colbers
Published 2020

Efavirenz pharmacokinetics during the third trimester of pregnancy and postpartum

by Tim R. Cressey, Alice Stek, Edmund Capparelli, Chureeratana Bowonwatanuwong, Sinart Prommas, Pannee Sirivatanapa, Prapap Yuthavisuthi, Chanon Neungton, Yanling Huo, Elizabeth Smith, Brookie M. Best, Mark Mirochnick
Published 2018

Pharmacokinetics of once versus twice daily darunavir in pregnant HIV-infected women

by Alice Stek, Brookie M. Best, Jiajia Wang, Edmund V. Capparelli, Sandra K. Burchett, Regis Kreitchmann, Kittipong Rungruengthanakit, Tim R. Cressey, Lynne M. Mofenson, Elizabeth Smith, David Shapiro, Mark Mirochnick
Published 2018

Pharmacokinetics of once versus twice daily darunavir in pregnant HIV-infected women

by Alice Stek, Brookie M. Best, Jiajia Wang, Edmund V. Capparelli, Sandra K. Burchett, Regis Kreitchmann, Kittipong Rungruengthanakit, Tim R. Cressey, Lynne M. Mofenson, Elizabeth Smith, David Shapiro, Mark Mirochnick
Published 2018

Impact of body weight and missed doses on lopinavir concentrations with standard and increased lopinavir/ritonavir doses during late pregnancy

by Tim R. Cressey, Saik Urien, Edmund V. Capparelli, Brookie M. Best, Sudanee Buranabanjasatean, Aram Limtrakul, Boonsong Rawangban, Prapan Sabsanong, Jean Marc Treluyer, Gonzague Jourdain, Alice Stek, Marc Lallemant, Mark Mirochnick
Published 2018

Impact of body weight and missed doses on lopinavir concentrations with standard and increased lopinavir/ritonavir doses during late pregnancy

by Tim R. Cressey, Saik Urien, Edmund V. Capparelli, Brookie M. Best, Sudanee Buranabanjasatean, Aram Limtrakul, Boonsong Rawangban, Prapan Sabsanong, Jean Marc Treluyer, Gonzague Jourdain, Alice Stek, Marc Lallemant, Mark Mirochnick
Published 2018

Prediction of Maternal and Fetal Pharmacokinetics of Dolutegravir and Raltegravir Using Physiologically Based Pharmacokinetic Modeling

by Xiaomei I. Liu, Jeremiah D. Momper, Natella Y. Rakhmanina, Dionna J. Green, Gilbert J. Burckart, Tim R. Cressey, Mark Mirochnick, Brookie M. Best, John N. van den Anker, André Dallmann
Published 2020

Evaluating darunavir/ritonavir dosing regimens for HIV-positive pregnant women using semi-mechanistic pharmacokinetic modelling

by Stein Schalkwijk, Rob Ter Heine, Angela Colbers, Edmund Capparelli, Brookie M. Best, Tim R. Cressey, Rick Greupink, Frans G.M. Russel, José Moltó, Mark Mirochnick, Mats O. Karlsson, David M. Burger
Published 2019

Pharmacokinetics of an increased atazanavir dose with and without tenofovir during the third trimester of pregnancy

by Regis Kreitchmann, Brookie M. Best, Jiajia Wang, Alice Stek, Edmund Caparelli, D. Heather Watts, Elizabeth Smith, David E. Shapiro, Steve Rossi, Sandra K. Burchett, Elizabeth Hawkins, Mark Byroads, Tim R. Cressey, Mark Mirochnick
Published 2018

Pharmacokinetics of an increased atazanavir dose with and without tenofovir during the third trimester of pregnancy

by Regis Kreitchmann, Brookie M. Best, Jiajia Wang, Alice Stek, Edmund Caparelli, D. Heather Watts, Elizabeth Smith, David E. Shapiro, Steve Rossi, Sandra K. Burchett, Elizabeth Hawkins, Mark Byroads, Tim R. Cressey, Mark Mirochnick
Published 2018

Reduced indinavir exposure during pregnancy

by Tim R. Cressey, Brookie M. Best, Jullapong Achalapong, Alice Stek, Jiajia Wang, Nantasak Chotivanich, Prapap Yuthavisuthi, Pornnapa Suriyachai, Sinart Prommas, David E. Shapiro, D. Heather Watts, Elizabeth Smith, Edmund Capparelli, Regis Kreitchmann, Mark Mirochnick
Published 2018

Reduced indinavir exposure during pregnancy

by Tim R. Cressey, Brookie M. Best, Jullapong Achalapong, Alice Stek, Jiajia Wang, Nantasak Chotivanich, Prapap Yuthavisuthi, Pornnapa Suriyachai, Sinart Prommas, David E. Shapiro, D. Heather Watts, Elizabeth Smith, Edmund Capparelli, Regis Kreitchmann, Mark Mirochnick
Published 2018

Raltegravir pharmacokinetics during pregnancy

by D. Heather Watts, Alice Stek, Brookie M. Best, Jiajia Wang, Edmund V. Capparelli, Tim R. Cressey, Francesca Aweeka, Patty Lizak, Regis Kreitchmann, Sandra K. Burchett, David E. Shapiro, Elizabeth Hawkins, Elizabeth Smith, Mark Mirochnick
Published 2018

Raltegravir pharmacokinetics during pregnancy

by D. Heather Watts, Alice Stek, Brookie M. Best, Jiajia Wang, Edmund V. Capparelli, Tim R. Cressey, Francesca Aweeka, Patty Lizak, Regis Kreitchmann, Sandra K. Burchett, David E. Shapiro, Elizabeth Hawkins, Elizabeth Smith, Mark Mirochnick
Published 2018

A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women

by Stein Schalkwijk, Rob Ter Heine, Angela C. Colbers, Alwin D.R. Huitema, Paolo Denti, Kelly E. Dooley, Edmund Capparelli, Brookie M. Best, Tim R. Cressey, Rick Greupink, Frans G.M. Russel, Mark Mirochnick, David M. Burger
Published 2018

A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women

by Stein Schalkwijk, Rob Ter Heine, Angela C. Colbers, Alwin D.R. Huitema, Paolo Denti, Kelly E. Dooley, Edmund Capparelli, Brookie M. Best, Tim R. Cressey, Rick Greupink, Frans G.M. Russel, Mark Mirochnick, David M. Burger
Published 2018

Fosamprenavir with Ritonavir Pharmacokinetics during Pregnancy

by Ahizechukwu C. Eke, Jiajia Wang, Khadija Amin, David E. Shapiro, Alice Stek, Elizabeth Smith, Nahida Chakhtoura, Michael Basar, Kathleen George, Katherine M. Knapp, Esaú C. João, Kittipong Rungruengthanakit, Edmund Capparelli, Sandra Burchett, Mark Mirochnick, Brookie M. Best
Published 2020

Raltegravir versus efavirenz in antiretroviral-naive pregnant women living with HIV (NICHD P1081): an open-label, randomised, controlled, phase 4 trial

by Esaú C. João, R. Leavitt Morrison, David E. Shapiro, Nahida Chakhtoura, Maria Isabel S. Gouvèa, Maria de Lourdes B Teixeira, Trevon L. Fuller, Blandina T. Mmbaga, James S. Ngocho, Boniface N. Njau, Avy Violari, Ruth Mathiba, Zaynab Essack, Jose Henrique S. Pilotto, Luis Felipe Moreira, Maria Jose Rolon, Pedro Cahn, Sinart Prommas, Timothy R. Cressey, Kulkanya Chokephaibulkit, Peerawong Werarak, Lauren Laimon, Roslyn Hennessy, Lisa M. Frenkel, Patricia Anthony, Brookie M. Best, George K. Siberry, Mark Mirochnick
Published 2020

Pharmacokinetics of Rilpivirine in HIV-Infected Pregnant Women

by Anna H. Tran, Brookie M. Best, Alice Stek, Jiajia Wang, Edmund V. Capparelli, Sandra K. Burchett, Regis Kreitchmann, Kittipong Rungruengthanakit, Kathleen George, Tim R. Cressey, Nahida Chakhtoura, Elizabeth Smith, David E. Shapiro, Mark Mirochnick, Shelley Buschur, Chivon Jackson, Mary Paul, Donna McGregor, Ram Yogev, Rohit Kalra, Claudia Florez, Patricia Bryan, Monica Stone, Andrew D. Hull, Mary Caffery, Stephen A. Spector, Joan Wilson, Julieta Giner, Margaret A. Donnelly, Ellen R. Cooper, Debra A. McLaud, Lisa F. Tucker, Jane Hitti, Amanda Robson-Nuss, Ann J. Melvin, Margaret A. Keller, Michael A. Bolaris, Judy Hayes, Françoise Kamer, La Shonda Spencer, James Homans, Torri Metz, Jenna Wallace, Alisa Katai, Mariam Aziz, Maureen McNichols, Julie Schmidt, Diane Wara, Kristinalisa Maka, Deborah Cohan, Audra Deveikis, Jagmohan Batra, Janielle Jackson Alvarez, Michele Carter, Jaime Deville, Carla Janzen, Jenny Gutierrez, Martha Cavallo, Murli Purswani, Katherine M. Knapp, Nina Sublette, Thomas Wride
Published 2018

Pharmacokinetics and safety of maraviroc in neonates

by Julia C. Rosebush, Brookie M. Best, Ellen G. Chadwick, Kevin Butler, John Moye, Elizabeth Smith, Sarah Bradford, Christina A. Reding, Sisinyana R. Mathiba, Sherika Hanley, Mariam Aziz, James Homans, Edward P. Acosta, William Murtaugh, Manoli Vourvahis, Lynn McFadyen, Katy Hayward, Mark Mirochnick, Pearl Samson, Ntatule Hilda Ndiweni, Zaakirah Essack, Mandisa Nyati, Lorna Pillay, Rosemary Gazu, Natasha Pillay, Damien Sookoo, Kulkanya Chokephaibulkit, Supattra Rungmaitree, Keswadee Lapphra, Orasri Wittawatmongkol, Isaac Tsikhutsu, Edner Openda, Priscillah Bii, David Wekulo, Ellen Chadwick, Jessica D’Angelo, Margaret Ann Sanders, Alice Stek, Mikhaela Cielo, La Shonda Spencer, Yvonne Morales, Christiana Smith-Anderson, Kacey Navarro, Carrie Glenny, Elizabeth McFarland, R. N. Maureen McNichols, Julie Schmidt, Helen Cejtin, Ixchell Ortiz-Estes, Katherine Knapp, Nehali Patel, Patricia M. Flynn, Jill Utech, Kathleen George, Shane Reynolds, Terence Fenton, Michelle Hsu, Jamie Branco-Ricard, Victoria Wong, Barbara Heckman, Kyle Whitson, Shawn Ward, Navdeep K. Thoofer
Published 2022