Biomedical applications I: Delivery of drugs

by Spalluto, G., Federico, S., Cacciari, B., Bianco, A., Cheong, S.L., Prato, M.
Published 2014

Exploring the directionality of 5-substitutions in a new series of 5-alkylaminopyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine as a strategy to design novel human A3 adenosine recep...

by Federico, S., Ciancetta, A., Sabbadin, D., Paoletta, S., Pastorin, G., Cacciari, B., Klotz, K.N., Moro, S., Spalluto, G.
Published 2014

The significance of 2-furyl ring substitution with a 2-(para -substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA3 adenosine...

by Cheong, S.L., Dolzhenko, A., Kachler, S., Paoletta, S., Federico, S., Cacciari, B., Dolzhenko, A., Klotz, K.-N., Moro, S., Spalluto, G., Pastorin, G.
Published 2014

Combining selectivity and affinity predictions using an integrated Support Vector Machine (SVM) approach: An alternative tool to discriminate between the human adenosine A2A and A3...

by Michielan, L., Bolcato, C., Federico, S., Cacciari, B., Bacilieri, M., Klotz, K.-N., Kachler, S., Pastorin, G., Cardin, R., Sperduti, A., Spalluto, G., Moro, S.
Published 2014

Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists: A prelimina...

by Pastorin, G., Federico, S., Paoletta, S., Corradino, M., Cateni, F., Cacciari, B., Klotz, K.-N., Gao, Z.-G., Jacobson, K.A., Spalluto, G., Moro, S.
Published 2014

Synthesis and biological evaluation of a new series of 1, 2, 4-triazolo[1, 5-α]-1, 3, 5-triazines as human a 2a adenosine receptor antagonists with improved water solubility

by Federico, S., Paoletta, S., Cheong, S.L., Pastorin, G., Cacciari, B., Stragliotto, S., Norbert Klotz, K., Siegel, J., Gao, Z.-G., Jacobson, K.A., Moro, S., Spalluto, G.
Published 2014