THEMIS: A critical TCR signal regulator for ligand discrimination

by Gascoigne N.R.J, Acuto O.
Published 2016

Negative selection assay based on stimulation of T cell receptor transgenic thymocytes with peptide-MHC tetramers

by Rybakin V., Gascoigne N.R.J.
Published 2018

Cell type-specific regulation of immunological synapse dynamics by B7 ligand recognition

by Brzostek, J, Gascoigne, N.R.J, Rybakin, V
Published 2020

The ups and downs of metabolism during the lifespan of a t cell

by Balyan, R., Gautam, N., Gascoigne, N.R.J.
Published 2021

Taming the sentinels: Microbiome-derived metabolites and polarization of t cells

by Wojciech, L., Tan, K.S.W., Gascoigne, N.R.J.
Published 2021

Development of a screening strategy for new modulators of T cell receptor signaling and T cell activation

by Chen E.W., Brzostek J., Gascoigne N.R.J., Rybakin V.
Published 2019

A Dual Inhibitor of Cdc7/Cdk9 Potently Suppresses T Cell Activation

by Chen, E.W., Tay, N.Q., Brzostek, J., Gascoigne, N.R.J., Rybakin, V.
Published 2021

Single cell analysis of drug susceptibility of mycobacterium abscessus during macrophage infection

by Brzostek, J., Fatin, A., Chua, W.H., Tan, H.Y., Dick, T., Gascoigne, N.R.J.
Published 2021

Allelic Exclusion of TCR α-Chains upon Severe Restriction of Vα Repertoire

by Rybakin V., Westernberg L., Fu G., Kim H.-O., Ampudia J., Sauer K., Gascoigne N.R.J.
Published 2018

CD40L expression allows CD8+ T cells to promote their own expansion and differentiation through dendritic cells

by Tay, N.Q, Lee, D.C.P, Chua, Y.L, Prabhu, N, Gascoigne, N.R.J, Kemeny, D.M
Published 2020

In Silico Modeling of Itk Activation Kinetics in Thymocytes Suggests Competing Positive and Negative IP4 Mediated Feedbacks Increase Robustness

by Mukherjee S., Rigaud S., Seok S.-C., Fu G., Prochenka A., Dworkin M., Gascoigne N.R.J., Vieland V.J., Sauer K., Das J.
Published 2018

Erratum: In silico modeling of itk activation kinetics in thymocytes suggests competing positive and negative IP 4 mediated feedbacks increase robustness (PLoS ONE (2014) 9:1)

by Mukherjee S., Rigaud S., Seok S.-C., Fu G., Prochenka A., Dworkin M., Gascoigne N.R.J., Vieland V.J., Sauer K., Das J.
Published 2020

Identification of a novel lymphoid population in the murine epidermis

by Almeida, F.F, Tenno, M, Brzostek, J, Li, J.L, Allies, G, Hoeffel, G, See, P, Ng, L.G, Fehling, H.J, Gascoigne, N.R.J, Taniuchi, I, Ginhoux, F
Published 2020

Nonstimulatory peptide-MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling

by Zhao X., Sankaran S., Yap J., Too C.T., Ho Z.Z., Dolton G., Legut M., Ren E.C., Sewell A.K., Bertoletti A., MacAry P.A., Brzostek J., Gascoigne N.R.J.
Published 2019

Defining the structural basis for human leukocyte antigen reactivity in clinical transplantation

by Gu, Y., Koh, R.W.K., Lai, M.L., Pochinco, D., Teo, R.Z.C., Chan, M., Murali, T.M., Liew, C.W., Wong, Y.H., Gascoigne, N.R.J., Wood, K.J., Lescar, J., Nickerson, P., MacAry, P.A., Vathsala, A.
Published 2021

TCR-like antibodies mediate complement and antibody-dependent cellular cytotoxicity against Epstein-Barr virus-transformed B lymphoblastoid cells expressing different HLA-A?02 micr...

by Lai J., Choo J.A.L., Tan W.J., Too C.T., Oo M.Z., Suter M.A., Mustafa F.B., Srinivasan N., Chan C.E.Z., Lim A.G.X., Zhong Y., Chan S.H., Hanson B.J., Gascoigne N.R.J., MacAry P.A.
Published 2020