The immune response against flaviviruses

by Jose Luis Slon Campos, Juthathip Mongkolsapaya, Gavin R. Screaton
Published 2019

Sensing of Immature Particles Produced by Dengue Virus Infected Cells Induces an Antiviral Response by Plasmacytoid Dendritic Cells

by Elodie Décembre, Sonia Assil, Marine L B Hillaire, Wanwisa Dejnirattisai, Juthathip Mongkolsapaya, Gavin R. Screaton, Andrew D. Davidson, Marlène Dreux
Published 2018

Therapeutic and protective efficacy of a dengue antibody against Zika infection in rhesus monkeys

by Peter Abbink, Rafael A. Larocca, Wanwisa Dejnirattisai, Rebecca Peterson, Joseph P. Nkolola, Erica N. Borducchi, Piyada Supasa, Juthathip Mongkolsapaya, Gavin R. Screaton, Dan H. Barouch
Published 2019

Structural analysis of a dengue cross-reactive antibody complexed with envelope domain III reveals the molecular basis of cross-reactivity

by Claire M. Midgley, Aleksandra Flanagan, Hai Bac Tran, Wanwisa Dejnirattisai, Kriangkrai Chawansuntati, Amonrat Jumnainsong, Wiyada Wongwiwat, Thaneeya Duangchinda, Juthathip Mongkolsapaya, Jonathan M. Grimes, Gavin R. Screaton
Published 2018

High-avidity and potently neutralizing cross-reactive human monoclonal antibodies derived from secondary dengue virus infection

by Wen Yang Tsai, Chih Yun Lai, Yi Chieh Wu, Hong En Lin, Carolyn Edwards, Amonrat Jumnainsong, Srisakul Kliks, Scott Halstead, Juthathip Mongkolsapaya, Gavin R. Screaton, Wei Kung Wang
Published 2018

Dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus

by Wanwisa Dejnirattisai, Piyada Supasa, Wiyada Wongwiwat, Alexander Rouvinski, Giovanna Barba-Spaeth, Thaneeya Duangchinda, Anavaj Sakuntabhai, Van Mai Cao-Lormeau, Prida Malasit, Felix A. Rey, Juthathip Mongkolsapaya, Gavin R. Screaton
Published 2018

Author Correction: Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection (Nature Immunology, (2017), 18, 11, (1261-1269), 10.1...

by Estefania Fernandez, Wanwisa Dejnirattisai, Bin Cao, Suzanne M. Scheaffer, Piyada Supasa, Wiyada Wongwiwat, Prabagaran Esakky, Andrea Drury, Juthathip Mongkolsapaya, Kelle H. Moley, Indira U. Mysorekar, Gavin R. Screaton, Michael S. Diamond
Published 2020

Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins

by Max Renner, Wanwisa Dejnirattisai, Loïc Carrique, Itziar Serna Martin, Dimple Karia, Serban L. Ilca, Shu F. Ho, Abhay Kotecha, Jeremy R. Keown, Juthathip Mongkolsapaya, Gavin R. Screaton, Jonathan M. Grimes
Published 2022

Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection

by Estefania Fernandez, Wanwisa Dejnirattisai, Bin Cao, Suzanne M. Scheaffer, Piyada Supasa, Wiyada Wongwiwat, Prabagaran Esakky, Andrea Drury, Juthathip Mongkolsapaya, Kelle H. Moley, Indira U. Mysorekar, Gavin R. Screaton, Michael S. Diamond
Published 2018

Covalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitope

by Alexander Rouvinski, Wanwisa Dejnirattisai, Pablo Guardado-Calvo, Marie Christine Vaney, Arvind Sharma, Stéphane Duquerroy, Piyada Supasa, Wiyada Wongwiwat, Ahmed Haouz, Giovanna Barba-Spaeth, Juthathip Mongkolsapaya, Félix A. Rey, Gavin R. Screaton
Published 2018

Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics

by LIM XIN XIANG, SHU BO, ZHANG SHUIJUN, AARON TAN WAI KIT, Ng Thiam Seng, Lim Xin Ni, CHEW SHYN YUN VALERIE, Shi Jian, Gavin R. Screaton, Lok Shee Mei, Ganesh Srinivasan Anand
Published 2022

Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice

by Vanessa Salazar, Brett W. Jagger, Juthathip Mongkolsapaya, Katherine E. Burgomaster, Wanwisa Dejnirattisai, Emma S. Winkler, Estefania Fernandez, Christopher A. Nelson, Daved H. Fremont, Theodore C. Pierson, James E. Crowe, Gavin R. Screaton, Michael S. Diamond
Published 2020

Characterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus

by Max Renner, Aleksandra Flanagan, Wanwisa Dejnirattisai, Chunya Puttikhunt, Watchara Kasinrerk, Piyada Supasa, Wiyada Wongwiwat, Kriangkrai Chawansuntati, Thaneeya Duangchinda, Alison Cowper, Claire M. Midgley, Prida Malasit, Juha T. Huiskonen, Juthathip Mongkolsapaya, Gavin R. Screaton, Jonathan M. Grimes
Published 2018

Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy

by Alex W. Wessel, Nurgun Kose, Robin G. Bombardi, Vicky Roy, Warangkana Chantima, Juthathip Mongkolsapaya, Melissa A. Edeling, Christopher A. Nelson, Irene Bosch, Galit Alter, Gavin R. Screaton, David H. Fremont, James E. Crowe, Michael S. Diamond
Published 2020

Characterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus

by Max Renner, Aleksandra Flanagan, Wanwisa Dejnirattisai, Chunya Puttikhunt, Watchara Kasinrerk, Piyada Supasa, Wiyada Wongwiwat, Kriangkrai Chawansuntati, Thaneeya Duangchinda, Alison Cowper, Claire M. Midgley, Prida Malasit, Juha T. Huiskonen, Juthathip Mongkolsapaya, Gavin R. Screaton, Jonathan M. Grimes
Published 2019

A protective Zika virus E-dimer-based subunit vaccine engineered to abrogate antibody-dependent enhancement of dengue infection

by Jose Luis Slon-Campos, Wanwisa Dejnirattisai, Brett W. Jagger, César López-Camacho, Wiyada Wongwiwat, Lorellin A. Durnell, Emma S. Winkler, Rita E. Chen, Arturo Reyes-Sandoval, Felix A. Rey, Michael S. Diamond, Juthathip Mongkolsapaya, Gavin R. Screaton
Published 2020

Reduced neutralisation of SARS-CoV-2 omicron B.1.1.529 variant by post-immunisation serum

by Wanwisa Dejnirattisai, Robert H. Shaw, Piyada Supasa, Chang Liu, Arabella SV Stuart, Andrew J. Pollard, Xinxue Liu, Teresa Lambe, Derrick Crook, Dave I. Stuart, Juthathip Mongkolsapaya, Jonathan S. Nguyen-Van-Tam, Matthew D. Snape, Gavin R. Screaton
Published 2022

Structural flexibility of the macrophage dengue virus receptor CLEC5A: Implications for ligand binding and signaling

by Aleksandra A. Watson, Andrey A. Lebedev, Benjamin A. Hall, Angharad E. Fenton-May, Alexei A. Vagin, Wanwisa Dejnirattisai, James Felce, Juthathip Mongkolsapaya, Angelina S. Palma, Yan Liu, Ten Feizi, Gavin R. Screaton, Garib N. Murshudov, Christopher A. O'Callaghan
Published 2018

An in-depth analysis of original antigenic sin in dengue virus infection

by Claire M. Midgley, Martha Bajwa-Joseph, Sirijitt Vasanawathana, Wannee Limpitikul, Bridget Wills, Aleksandra Flanagan, Emily Waiyaiya, Hai Bac Tran, Alison E. Cowper, Pojchong Chotiyarnwong, Jonathan M. Grimes, Sutee Yoksan, Prida Malasit, Cameron P. Simmons, Juthathip Mongkolsapaya, Gavin R. Screaton
Published 2018

An in-depth analysis of original antigenic sin in dengue virus infection

by Claire M. Midgley, Martha Bajwa-Joseph, Sirijitt Vasanawathana, Wannee Limpitikul, Bridget Wills, Aleksandra Flanagan, Emily Waiyaiya, Hai Bac Tran, Alison E. Cowper, Pojchong Chotiyarnwon, Jonathan M. Grimes, Sutee Yoksan, Prida Malasit, Cameron P. Simmons, Juthathip Mongkolsapaya, Gavin R. Screaton
Published 2018