Effect of the molecular mobility of water adsorbed by disintegrants on storage-induced hydrolytic degradation of acetylsalicylic acid incorporated into tablets under humid conditio...

by Ougi, Kousuke, Okada, Kotaro, Leong, Kok Hoong, Hayashi, Yoshihiro, Kumada, Shungo, Onuki, Yoshinori
Published 2020

Characterization of the salt and free base of active pharmaceutical ingredients based on NMR relaxometry measured by time domain NMR

by Chiba, Yuya, Okada, Kotaro, Hayashi, Yoshihiro, Leong, Kok Hoong, Kumada, Shungo, Onuki, Yoshinori
Published 2022

Effect of Different Direct Compaction Grades of Mannitol on the Storage Stability of Tablet Properties Investigated Using a Kohonen Self-Organizing Map and Elastic Net Regression M...

by Kosugi, Atsushi, Leong, Kok Hoong, Urata, Eri, Hayashi, Yoshihiro, Kumada, Shungo, Okada, Kotaro, Onuki, Yoshinori
Published 2020

A precise prediction method for the properties of API-containing tablets based on data from placebo tablets

by Hayashi, Yoshihiro, Shirotori, Kaede, Kosugi, Atsushi, Kumada, Shungo, Leong, Kok Hoong, Okada, Kotaro, Onuki, Yoshinori
Published 2020

Characterization of Powder- and Tablet Properties of Different Direct Compaction Grades of Mannitol Using a Kohonen Self-organizing Map and a Lasso Regression Model

by Kosugi, Atsushi, Leong, Kok Hoong, Tsuji, Hinako, Hayashi, Yoshihiro, Kumada, Shungo, Okada, Kotaro, Onuki, Yoshinori
Published 2020

A Time-Domain NMR Study of the State of Water in Wet Granules with Different Fillers and Its Contribution to the Wet Granulation Process and to the Characteristics of Granules

by Ito, Terushi, Okada, Kotaro, Leong, Kok Hoong, Hirai, Daijiro, Hayashi, Yoshihiro, Kumada, Shungo, Kosugi, Atsushi, Onuki, Yoshinori
Published 2019

Time-domain NMR analysis for the determination of water content in pharmaceutical ingredients and wet granules

by Ohgi, Kosuke, Hayashi, Yoshihiro, Tsuji, Takahiro, Ito, Terushi, Leong, Kok Hoong, Usuda, Shui, Kumada, Shungo, Okada, Kotaro, Onuki, Yoshinori
Published 2021