MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma

by Kong, Li Ren, Chua, Kian Ngiap, Sim, Wen Jing, Ng, Hsien Chun, Bi, Chonglei, Ho, Jingshan, Nga, Min En, Pang, Yin Huei, Ong, Weijie Richard, Soo, Ross Andrew, Huynh, The Hung, Chng, Wee Joo, Thiery, Jean-Paul, Goh, Boon Cher
Published 2020

A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma

by Kong, Li Ren, Salleh, Nur Afiqah Binte Mohamed, Ong, Richard Weijie, Tan, Tuan Zea, Syn, Nicholas L, Goh, Robby Miguel, Fhu, Chee Wei, Tan, Daniel SW, Iyer, N Gopalakrishna, Kannan, Srinivasaraghavan, Verma, Chandra S, Lim, Yaw Chyn, Soo, Ross, Ho, Jingshan, Huang, Yiqing, Lim, Joline SJ, Yan, Benedict Junrong, Nga, Min En, Lim, Seng Gee, Koeffler, H Phillip, Lee, Soo Chin, Kappei, Dennis, Hung, Huynh The, Goh, Boon Cher
Published 2020

A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in...

by Ho, Jingshan, Heong, Valerie, Yong, Wei Peng, Soo, Ross, Chee, Cheng Ean, Wong, Andrea, Sundar, Raghav, Thian, Yee Liang, Gopinathan, Anil, Pang, Mei Yan, Koe, Priscillia, Jeraj, Santhiay Nathan, Soe, Phyu Pyar, Soe, Mu Yar, Tang, Tiffany, Ng, Matthew CH, Tai, David WM, Tan, Tira JY, Xu, Hongmei, Chang, Hua, Landesman, Yosef, Shah, Jatin, Shacham, Sharon, Lee, Soo Chin, Tan, Daniel SW, Goh, Boon Cher, Tan, David SP
Published 2022