Insights from the growing up in singapore towards healthy outcomes (GUSTO) cohort study

by Soh S.-E., Chong Y.-S., Kwek K., Saw S.-M., Meaney M.J., Gluckman P.D., Holbrook J.D., Godfrey K.M., The GUSTO Study Group
Published 2021

Toxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination

by Dogra S., Sakwinska O., Soh S.-E., Ngom-Bru C., Bruck W.M., Berger B., Brussow H., Lee Y.S., Yap F., Chong Y.-S., Godfrey K.M., Holbrook J.D.
Published 2016

Global DNA Hypermethylation in Down Syndrome Placenta

by Jin S., Lee Y.K., Lim Y.C., Zheng Z., Lin X.M., Ng D.P.Y., Holbrook J.D., Law H.Y., Kwek K.Y.C., Yeo G.S.H., Ding C.
Published 2019

Does the maternal vaginal microbiota play a role in seeding the microbiota of neonatal gut and nose?

by Sakwinska O., Foata F., Berger B., Brüssow H., Combremont S., Mercenier A., Dogra S., Soh S.-E., Yen J.C.K., Heong G.Y.S., Lee Y.S., Yap F., Meaney M.J., Chong Y.-S., Godfrey K.M., Holbrook J.D.
Published 2018

COMT haplotypes modulate associations of antenatal maternal anxiety and neonatal cortical morphology

by Qiu A., Tuan T.A., Ong M.L., Li Y., Chen H., Rifkin-Graboi A., Broekman B.F.P., Kwek K., Saw S.-M., Chong Y.-S., Gluckman P.D., Fortier M.V., Holbrook J.D., Meaney M.J.
Published 2021

The influence of CHRNA4, COMT, and maternal sensitivity on orienting and executive attention in 6-month-old infants

by Quan, J., Ong, M.-L., Bureau, J.-F., Sim, L.W., Sanmugam, S., Abdul Malik, A.B., Wong, E., Wong, J., Chong, Yap Seng, Qiu, A., Holbrook, J.D., Rifkin-Graboi, A., Saw, Seang Mei, Kwek, K., Qiu, Anqi
Published 2017

Ratio of Klebsiella/Bifidobacterium in early life correlates with later development of paediatric allergy

by Low J.S.Y., Soh S.-E., Lee Y.K., Kwek K.Y.C., Holbrook J.D., Van der Beek E.M., Shek L.P., Goh A.E.N., Teoh O.H., Godfrey K.M., Chong Y.-S., Knol J., Lay C.
Published 2018

Parkin pathway activation mitigates glioma cell proliferation and predicts patient survival

by Yeo, C.W.S., Ng, F.S.L., Chai, C., Tan, J.M.M., Koh, G.R.H., Chong, Y., Koh, L.W.H., Foong, C.S.F., Sandanaraj, E., Holbrook, J.D., Ang, B.-T., Takahashi, R., Tang, C., Lim, K.-L.
Published 2014

Molecular pathways reflecting poor intrauterine growth are found in Wharton's jelly-derived mesenchymal stem cells

by Sukarieh R., Joseph R., Leow S.C., Li Y., Löffler M., Aris I.M., Tan J.H., Teh A.L., Chen L., Holbrook J.D., Ng K., Lee Y.S., Chong Y.S., Summers S.A., Gluckman P.D., Stünkel W.
Published 2021

MC3R gene polymorphisms are associated with early childhood adiposity gain and infant appetite in an Asian population

by Aris I.M., Tint M.T., Teh A.L., Holbrook J.D., Quah P.L., Chong M.F.-F., Lin X., Soh S.E., Saw S.-M., Kwek K., Godfrey K.M., Gluckman P.D., Chong Y.S., Lek N., Yap F., Lee Y.S.
Published 2018

Alterations to DNA methylation and expression of CXCL14 are associated with suboptimal birth outcomes

by Cheong C.Y., Chng K., Lim M.K., Amrithraj A.I., Joseph R., Sukarieh R., Chee Tan Y., Chan L., Tan J.H., Chen L., Pan H., Holbrook J.D., Meaney M.J., Seng Chong Y., Gluckman P.D., Stünkel W.
Published 2021

Comparison of Methyl-capture Sequencing vs. Infinium 450K methylation array for methylome analysis in clinical samples

by Teh A.L., Pan H., Lin X., Lim Y.I.[student], Patro C.P.K., Cheong C.Y., Gong M., MacIsaac J.L., Kwoh C.-K., Meaney M.J., Kobor M.S., Chong Y.-S., Gluckman P.D., Holbrook J.D., Karnani N.
Published 2018

Measuring the methylome in clinical samples: Improved processing of the infinium human methylation450 beadchip array

by Pan H., Chen L., Dogra S., Teh A.L., Tan J.H., Lim Y.I., Lim Y.C., Jin S., Lee Y.K., Ng P.Y., Ong M.L., Barton S., Chong Y.-S., Meaney M.J., Gluckman P.D., Stunkel W., Ding C., Holbrook J.D.
Published 2021

Transcriptome changes affecting Hedgehog and cytokine signalling in the umbilical cord: Implications for disease risk

by Stünkel, W., Pan, H., Chew, S.B., Tng, E., Tan, J.H., Chen, L., Joseph, R., Cheong, C.Y., Ong, M.-L., Lee, Y.S., Chong, Y.-S., Saw, S.M., Meaney, M.J., Kwek, K., Sheppard, A.M., Gluckman, P.D., Holbrook, J.D.
Published 2014

Neonatal amygdalae and hippocampi are influenced by genotype and prenatal environment, and reflected in the neonatal DNA methylome

by Ong M.-L., Tuan T.A., Poh J., Teh A.L., Chen L., Pan H., MacIsaac J.L., Kobor M.S., Chong Y.S., Kwek K., Saw S.M., Godfrey K.M., Gluckman P.D., Fortier M.V., Karnani N., Meaney M.J., Qiu A., Holbrook J.D.
Published 2021

ST3GAL1-Associated Transcriptomic Program in Glioblastoma Tumor Growth, Invasion, and Prognosis

by Chong Y.K., Sandanaraj E., Koh L.W.H., Thangaveloo M., Tan M.S.Y., Koh G.R.H., Toh T.B., Lim G.G.Y., Holbrook J.D., Kon O.L., Nadarajah M., Ng I., Ng W.H., Tan N.S., Lim K.L., Tang Soo Leng Carol, Ang B.T.
Published 2018

DNA methylome variation in a perinatal nurse-visitation program that reduces child maltreatment: A 27-year follow-up

by O'Donnell, K.J, Chen, L, MacIsaac, J.L, McEwen, L.M, Nguyen, T, Beckmann, K, Zhu, Y, Chen, L.M, Brooks-Gunn, J, Goldman, D, Grigorenko, E.L, Leckman, J.F, Diorio, J, Karnani, N, Olds, D.L, Holbrook, J.D, Kobor, M.S, Meaney, M.J
Published 2020

Choice of surrogate tissue influences neonatal EWAS findings

by Lin X., Teh A.L., Chen L., Lim I.Y., Tan P.F., MacIsaac J.L., Morin A.M., Yap F., Tan K.H., Saw S.M., Lee Y.S., Holbrook J.D., Godfrey K.M., Meaney M.J., Kobor M.S., Chong Y.S., Gluckman P.D., Karnani N.
Published 2019

HIF3A association with adiposity: The story begins before birth

by Pan H., Lin X., Wu Y., Chen L., Teh A.L., Soh S.E., Lee Y.S., Tint M.T., Macisaac J.L., Morin A.M., Tan K.H., Yap F., Saw S.M., Kobor M.S., Meaney M.J., Godfrey K.M., Chong Y.-S., Gluckman P.D., Karnani N., Holbrook J.D.
Published 2021

Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism influences the association of the methylome with maternal anxiety and neonatal brain volumes

by Chen L., Pan H., Tuan T.A., Teh A.L., Macisaac J.L., Mah S.M., Mcewen L.M., Li Y., Chen H., Broekman B.F.P., Buschdorf J.P., Chong Y.S., Kwek K., Saw S.M., Gluckman P.D., Fortier M.V., Rifkin-Graboi A., Kobor M.S., Qiu A., Meaney M.J., Holbrook J.D.
Published 2021