Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor

by Janes, M.R., Limon, J.J., So, L., Chen, J., Lim, R.J., Chavez, M.A., Vu, C., Lilly, M.B., Mallya, S., Ong, S.T., Konopleva, M., Martin, M.B., Ren, P., Liu, Y., Rommel, C., Fruman, D.A.
Published 2016

Pronounced hypoxia in models of murine and human leukemia: High efficacy of hypoxia-activated prodrug PR-104

by Benito J., Shi Y., Szymanska B., Carol H., Boehm I., Lu H., Konoplev S., Fang W., Zweidler-McKay P.A., Campana D., Borthakur G., Bueso-Ramos C., Shpall E., Thomas D.A., Jordan C.T., Kantarjian H., Wilson W.R., Lock R., Andreeff M., Konopleva M.
Published 2018