Mesenchymal stem cell exosome: A novel stem cell-based therapy for cardiovascular disease

by Lai, R.C., Chen, T.S., Lim, S.K.
Published 2014

MSC exosome works through a protein-based mechanism of action

by Toh W.S., Lai R.C., Zhang B., Lim S.K.
Published 2019

Immunotherapeutic potential of extracellular vesicles

by Zhang, B, Yin, Y, Lai, R.C, Lim, S.K
Published 2020

MSC exosome as a cell-free MSC therapy for cartilage regeneration: Implications for osteoarthritis treatment

by Toh W.S., Lai R.C., Hui J.H.P., Lim S.K.
Published 2018

Mesenchymal stem cell exosome ameliorates reperfusion injury through proteomic complementation

by Lai, R.C., Yeo, R.W.Y., Tan, K.H., Lim, S.K.
Published 2014

Exosomes for drug delivery - A novel application for the mesenchymal stem cell

by Lai, R.C., Yeo, R.W.Y., Tan, K.H., Lim, S.K.
Published 2014

Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models

by Tan C.Y., Lai R.C., Wong W., Dan Y.Y., Lim S.-K., Ho H.K.
Published 2020

Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs

by Chen, T.S., Lai, R.C., Lim, S.K., Lee, M.M., CHOO BOON HWA,ANDRE, Lee, C.N.
Published 2011

Mesenchymal stem cell: An efficient mass producer of exosomes for drug delivery

by Yeo, R.W.Y., Lai, R.C., Zhang, B., Tan, S.S., Yin, Y., Teh, B.J., Lim, S.K.
Published 2014

Addendum to "Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury" [Stem Cell Research 4 (2010) 214-222] (DOI:10.1016/j.scr.2009.12.003)

by Lai, R.C., Chen, T.S., Lim, S.K., Lai, R.C., Arslan, F., Timmers, L., Pasterkamp, G., de, Kleijn D.P.V., Lee, M.M., Sze, S.K., Choo, A., Salto-Tellez, M., Lee, C.N., El, Oakley R.M., de, Kleijn D.P.V.
Published 2011

Systemic mesenchymal stem cell-derived exosomes reduce myocardial infarct size: Characterization with MRI in a porcine model

by Charles, C.J., Li, R.R., Yeung, T., Mazlan, S.M.I., Lai, R.C., Dekleijn, D.P.V., Lim, S., Richards, A.M.
Published 2021

Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs

by Chen, T.S., Arslan, F., Yin, Y., Tan, S.S., Lai, R.C., Choo, A.B.H., Padmanabhan, J., Lee, C.N., de Kleijn, D.P.V., Lim, S.K.
Published 2014

Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling a...

by Arslan, F., Lai, R.C., Smeets, M.B., Akeroyd, L., Choo, A., Aguor, E.N.E., Timmers, L., van Rijen, H.V., Doevendans, P.A., Pasterkamp, G., Lim, S.K., de Kleijn, D.P.
Published 2014

Elucidating the secretion proteome of human embryonic stem cell-derived mesenchymal stem cells

by Sze, S.K., de, Kleijn D.P.V., Tan, E.K.W., Yeo, K.S., Lian, Q., Lim, S.-K., Low, T.Y., Mitchell, W., Lai, R.C., Zhao, H., Lee, C.N., El, Oakley R.M.
Published 2011

Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

by Lai, R.C., Arslan, F., Lee, M.M., Sze, N.S.K., Choo, A., Chen, T.S., Salto-Tellez, M., Timmers, L., Lee, C.N., El, Oakley R.M., Pasterkamp, G., de, Kleijn D.P.V., Lim, S.K.
Published 2011

Addendum to Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury [Stem Cell Research, 4, (2010), 214-222]

by Lai, R.C., Arslan, F., Lee, M.M., Sze, S.K., CHOO BOON HWA,ANDRE, Chen, T.S., Salto-Tellez, M., Timmers, L., Lee, C.N., El Oakley, R.M., Pasterkamp, G., de Kleijn, D.P.V., Lim, S.K.
Published 2014

Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction

by Timmers, L., Lim, S.K., Hoefer, I.E., Arslan, F., Lai, R.C., van Oorschot, A.A.M., Goumans, M.J., Strijder, C., Sze, S.K., Choo, A., Piek, J.J., Doevendans, P.A., Pasterkamp, G., de Kleijn, D.P.V.
Published 2014

Derivation and characterization of human fetal MSCs: An alternative cell source for large-scale production of cardioprotective microparticles

by Lai, R.C., Tan, S.S., Chen, T.S., Teh, B.J., Sidik, H., Lim, S.K., Arslan, F., Pasterkamp, G., de, Kleijn D.P.V., Tan, B., Tanavde, V., CHOO BOON HWA,ANDRE, Lee, M.M., Eng, J.K.L., Hwang, W.S., Lee, C.N., Oakley, R.M.E., Tan, K.H.
Published 2011