Human antibodies stop dengue virus by jamming its mechanics

by Lok, S.-M.
Published 2016

Capsid protein is central to the birth of flavivirus particles

by Tan, T.Y., Fibriansah, G., Lok, S.-M.
Published 2021

MIP-1α and MIP-1β induction by dengue virus

by Lok, S.M., Ng, M.L., Aaskov, J.
Published 2016

Near-atomic resolution cryo-electron microscopic structure of dengue serotype 4 virus

by Kostyuchenko, V.A., Chew, P.L., Ng, T.-S., Lok, S.-M.
Published 2016

Immature and mature dengue serotype 1 virus structures provide insight into the maturation process

by Kostyuchenko, V.A., Zhang, Q., Tan, J.L., Ng, T.-S., Lok, S.-M.
Published 2016

Isomaltulose synthase (PalI) of Klebsiella sp. LX3: Crystal structure and implication of mechanism

by Zhang, D., Li, N., Lok, S.-M., Swaminathan, K., Zhang, L.-H.
Published 2012

Structure and function comparison of Micropechis ikaheka snake venom phospholipase A2 isoenzymes

by Lok, S.-M., Gao, R., Rouault, M., Lambeau, G., Gopalakrishnakone, P., Swaminathan, K.
Published 2014

Structural changes in dengue virus when exposed to a temperature of 37°C

by Fibriansah, G., Ng, T.-S., Kostyuchenko, V.A., Lee, J., Lee, S., Wang, J., Lok, S.-M.
Published 2016

Conformational changes in intact dengue virus reveal serotype-specific expansion

by Lim, X.-X, Chandramohan, A, Lim, X.Y.E, Bag, N, Sharma, K.K, Wirawan, M, Wohland, T, Lok, S.-M, Anand, G.S
Published 2020

Atomic structure of the 75 MDa extremophile Sulfolobus turreted icosahedral virus determined by CryoEM and X-ray crystallography

by Veesler, D., Ng, T.-S., Sendamarai, A.K., Eilers, B.J., Lawrence, C.M., Lok, S.-M., Young, M.J., Johnson, J.E., Fu, C.-Y.
Published 2016

Neutralization mechanism of a highly potent antibody against Zika virus

by Zhang, S, Kostyuchenko, V.A, Ng, T.-S, Lim, X.-N, Ooi, J.S.G, Lambert, S, Tan, T.Y, Widman, D.G, Shi, J, Baric, R.S, Lok, S.-M
Published 2020

Resistance analysis of an antibody that selectively inhibits dengue virus serotype-1

by Zou, G., Kukkaro, P., Lok, S.-M., Ng, J.K.W., Tan, G.K., Hanson, B.J., Alonso, S., MacAry, P.A., Shi, P.-Y.
Published 2016

A Human Antibody Neutralizes Different Flaviviruses by Using Different Mechanisms

by Zhang, S., Loy, T., Ng, T.-S., Lim, X.-N., Chew, S.-Y.V., Tan, T.Y., Xu, M., Kostyuchenko, V.A., Tukijan, F., Shi, J., Fink, K., Lok, S.-M.
Published 2021

Capsid protein structure in Zika virus reveals the flavivirus assembly process

by Tan, T.Y., Fibriansah, G., Kostyuchenko, V.A., Ng, T.-S., Lim, X.-X., Zhang, S., Lim, X.-N., Wang, J., Shi, J., Morais, M.C., Corti, D., Lok, S.-M.
Published 2021

Structural optimization and de novo design of dengue virus entry inhibitory peptides

by Costin J.M., Jenwitheesuk E., Lok S.-M., Hunsperger E., Conrads K.A., Fontaine K.A., Rees C.R., Rossmann M.G., Isern S., Samudrala R., Michael S.F.
Published 2019

A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins

by Fibriansah G., Tan J.L., Smith S.A., De Alwis R., Ng T.-S., Kostyuchenko V.A., Jadi R.S., Kukkaro P., De Silva A.M., Crowe J.E., Lok S.-M.
Published 2016

Molecular basis of dengue virus serotype 2 morphological switch from 29°C to 37°C

by Lim, X.-N., Shan, C., Marzinek, J.K., Dong, H., Ng, T.S., Ooi, J.S.G., Fibriansah, G., Wang, J., Verma, C.S., Bond, P.J., Shi, P.-Y., Lok, S.-M.
Published 2021

2′-O methylation of internal adenosine by flavivirus NS5 methyltransferase

by Dong, H., Chang, D.C., Hua, M.H.C., Lim, S.P., Chionh, Y.H., Hia, F., Lee, Y.H., Kukkaro, P., Lok, S.-M., Dedon, P.C., Shi, P.-Y.
Published 2016

A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface

by Fibriansah G., Tan J.L., Smith S.A., de Alwis A.R., Ng T.-S., Kostyuchenko V.A., Ibarra K.D., Wang J., Harris E., de Silva A., Crowe J.E., Lok S.-M.
Published 2020

A human PrM antibody that recognizes a novel cryptic epitope on dengue E glycoprotein

by Chan, A.H.Y., Tan, H.C., Chow, A.Y., Lim, A.P.C., Lok, S.M., Moreland, N.J., Vasudevan, S.G., MacAry, P.A., Ooi, E.E., Hanson, B.J.
Published 2014