Protein kinase C δ associates with the interleukin-6 receptor subunit glycoprotein (gp) 130 via Stat3 and enhances Stat3-gp 130 interaction

by Novotny-Diermayr, V., Zhang, T., Gu, L., Cao, X.
Published 2013

Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling by LMO4 interaction

by Novotny-Diermayr, V., Lin, B., Gu, L., Cao, X.
Published 2013

Pacritinib (SB1518), a JAK2/FLT3 inhibitor for the treatment of acute myeloid leukemia

by Hart, S., Goh, K.C., Novotny-Diermayr, V., Tan, Y.C., Madan, B., Amalini, C., Ong, L.C., Kheng, B., Cheong, A., Zhou, J., Chng, W.J., Wood, J.M.
Published 2014

Pharmacodynamic evaluation of the target efficacy of SB939, an oral HDAC inhibitor with selectivity for tumor tissue

by Novotny-Diermayr, V., Sausgruber, N., Loh, Y.K., Pasha, M.K., Jayaraman, R., Hentze, H., Yong, W.-P., Goh, B.-C., Toh, H.-C., Ethirajulu, K., Zhu, J., Wood, J.M.
Published 2014

First-in-Human, Healthy Volunteers Integrated Protocol of ETC-206, an Oral Mnk 1/2 Kinase Inhibitor Oncology Drug

by Teneggi, V, Novotny-Diermayr, V, Lee, LH, Yasin, M, Yeo, P, Ethirajulu, K, Gan, SBH, Blanchard, SE, Nellore, R, Umrani, DN, Gomeni, R, Teck, DLW, Li, G, Lu, QS, Cao, Y, Matter, A
Published 2021

Phase I and pharmacodynamic study of an orally administered novel inhibitor of histone deacetylases, SB939, in patients with refractory solid malignancies

by Yong, W.P., Goh, B.C., Soo, R.A., Toh, H.C., Ethirajulu, K., Wood, J., Novotny-Diermayr, V., Lee, S.C., Yeo, W.L., Chan, D., Lim, D., Seah, E., Lim, R., Zhu, J.
Published 2014

VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer

by Hart, S., Novotny-Diermayr, V., Goh, K.C., Williams, M., Tan, Y.C., Ong, L.C., Cheong, A., Ng, B.K., Amalini, C., Madan, B., Nagaraj, H., Jayaraman, R., Pasha, K.M., Ethirajulu, K., Chng, W.J., Mustafa, N., Goh, B.C., Benes, C., McDermott, U., Garnett, M., Dymock, B., Wood, J.M.
Published 2016

Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine

by Skibinski, D.A.G, Jones, L.A, Zhu, Y.O, Xue, L.W, Au, B, Lee, B, Naim, A.N.M, Lee, A, Kaliaperumal, N, Low, J.G.H, Lee, L.S, Poidinger, M, Saudan, P, Bachmann, M, Ooi, E.E, Hanson, B.J, Novotny-Diermayr, V, Matter, A, Fairhurst, A.-M, Hibberd, M.L, Connolly, J.E
Published 2020