Generating specificity and diversity in the transcriptional response to hypoxia

by Lendahl, U., Lee, K.L., Yang, H., Poellinger, L.
Published 2014

Erratum to: Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression (Scientific Reports, (2017), 7, 1, (7190), 10.1038/s41598...

by Sun W., Kato H., Kitajima S., Lee K.L., Gradin K., Okamoto T., Poellinger L.
Published 2020

HIF-dependent and reversible nucleosome disassembly in hypoxia-inducible gene promoters

by Suzuki N., Vojnovic N., Lee K.-L., Yang H., Gradin K., Poellinger L.
Published 2020

Dual inhibition of Src and GSK3 maintains mouse embryonic stem cells, whose differentiation is mechanically regulated by Src signaling

by Shimizu, T., Ueda, J., Ho, J.C., Iwasaki, K., Poellinger, L., Harada, I., Sawada, Y.
Published 2014

Regulation of CDKN2B expression by interaction of Arnt with Miz-1 - a basis for functional integration between the HIF and Myc gene regulatory pathways

by Aesoy, R., Gradin, K., Aasrud, K.S., Hoivik, E.A., Ruas, J.L., Poellinger, L., Bakke, M.
Published 2014

Xenobiotics and loss of cell adhesion drive distinct transcriptional outcomes by aryl hydrocarbon receptor signaling

by Hao, N., Lee, K.L., Furness, S.G.B., Bosdotter, C., Poellinger, L., Whitelaw, M.L.
Published 2014

Hypoxia regulates microRNA expression in the human carotid body

by Mkrtchian S., Lee K.L., Kåhlin J., Ebberyd A., Poellinger L., Fagerlund M.J., Eriksson L.I.
Published 2020

Complex regulation of the transactivation function of hypoxia-inducible factor-1αby direct interaction with two distinct domains of the creb-binding protein/p300

by Ruas, J.L., Berchner-Pfannschmidt, U., Malik, S., Gradin, K., Fandrey, J., Roeder, R.G., Pereira, T., Poellinger, L.
Published 2014

Hypoxia-induced and calpain-dependent cleavage of filamin A regulates the hypoxic response

by Zheng, X., Zhou, A.-X., Rouhi, P., Uramoto, H., Borén, J., Cao, Y., Pereira, T., Akyürek, L.M., Poellinger, L.
Published 2014

Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state

by Lanner, F., Lee, K.L., Sohl, M., Holmborn, K., Yang, H., Wilbertz, J., Poellinger, L., Rossant, J., Farnebo, F.
Published 2014

GENETIC ANALYSIS OF HYPOXIA INDUCIBLE FACTOR-2 ALPHA IN LUNG CANCER: OJ-019

by PUTRA AC, EGUCHI H, LEE KL, YAMANE Y, GUSTINE E, NISHIYAMA M, ISOBE T, HIYAMA KEIKO, POELLINGER L, TANIMOTO K
Published 2020

Graded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions

by Lee, K.L., Lim, S.K., Orlov, Y.L., Yit, L.Y., Yang, H., Ang, L.T., Poellinger, L., Lim, B.
Published 2014

Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition

by Ng K.P., Manjeri A., Lee K.L., Huang W., Tan S.Y., Chuah C.T.H., Poellinger L., Ong S.T.
Published 2020

The Krüppel-like zinc finger transcription factor, GLI-similar 1, is regulated by hypoxia-inducible factors via non-canonical mechanisms

by Khalesi, E., Nakamura, H., Lee, K.L., Putra, A.C., Fukazawa, T., Kawahara, Y., Makino, Y., Poellinger, L., Yuge, L., Tanimoto, K.
Published 2014

Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells

by Kitajima S., Lee K.L., Fujioka M., Sun W., You J., Chia G.S., Wanibuchi H., Tomita S., Araki M., Kato H., Poellinger L.
Published 2020

Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cells

by Main, H., Lee, K.L., Yang, H., Haapa-Paananen, S., Edgren, H., Jin, S., Sahlgren, C., Kallioniemi, O., Poellinger, L., Lim, B., Lendahl, U.
Published 2014

Non-canonical HIF-2α function drives autonomous breast cancer cell growth via an AREG-EGFR/ErbB4 autocrine loop

by Stiehl, D.P., Bordoli, M.R., Abreu-Rodríguez, I., Wollenick, K., Schraml, P., Gradin, K., Poellinger, L., Kristiansen, G., Wenger, R.H.
Published 2014

PIAS4 is an activator of hypoxia signalling via VHL suppression during growth of pancreatic cancer cells

by Chien, W., Lee, K.L., Ding, L.W., Wuensche, P., Kato, H., Doan, N.B., Poellinger, L., Said, J.W., Koeffler, H.P.
Published 2014

Hypoxia-induced arterial differentiation requires adrenomedullin and notch signaling

by Lanner, F., Lee, K.L., Ortega, G.C., Sohl, M., Li, X., Jin, S., Hansson, E.M., Claesson-Welsh, L., Poellinger, L., Lendahl, U., Farnebo, F.
Published 2014

Acute hypoxia induces apoptosis of pancreatic β-cell by activation of the unfolded protein response and upregulation of CHOP

by Zheng, X., Zheng, X., Wang, X., Ma, Z., Gupta Sunkari, V., Botusan, I., Takeda, T., Björklund, A., Inoue, M., Catrina, S.-B., Brismar, K., Poellinger, L., Pereira, T.S.
Published 2014