Prolyl isomerase Pin1: A catalyst for oncogenesis and a potential therapeutic target in cancer

by Ryo, A, Liou, Y.-C, Lu, K.P, Wulf, G
Published 2020

Regulation of NF-κB Signaling by Pin1-Dependent Prolyl Isomerization and Ubiquitin-Mediated Proteolysis of p65/RelA

by Ryo, A., Suizu, F., Perrem, K., Liou, Y.-C., Wulf, G., Lu, K.P., Yoshida, Y., Rottapel, R., Yamaoka, S.
Published 2013

Establishment of a robust dengue virus NS3-NS5 binding assay for identification of protein-protein interaction inhibitors

by Takahashi, H., Takahashi, C., Moreland, N.J., Chang, Y.-T., Sawasaki, T., Ryo, A., Vasudevan, S.G., Suzuki, Y., Yamamoto, N.
Published 2014

Interferon-induced SCYL2 limits release of HIV-1 by triggering PP2A-mediated dephosphorylation of the viral protein Vpu

by Miyakawa, K., Sawasaki, T., Matsunaga, S., Tokarev, A., Quinn, G., Kimura, H., Nomaguchi, M., Adachi, A., Yamamoto, N., Guatelli, J., Ryo, A.
Published 2016

A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx

by Ryo, A., Hirai, A., Nishi, M., Liou, Y.-C., Perrem, K., Lin, S.-C., Hirano, H., Lee, S.W., Aoki, I.
Published 2014

Pin1 catalyzes conformational changes of Thr-187 in p27Kip1 and mediates its stability through a polyubiquitination process

by Zhou, W., Yang, Q., Low, C.B., Karthik, B.C., Wang, Y., Ryo, A., Yao, S.Q., Yang, D., Liou, Y.-C.
Published 2014

Prolyl-isomerase Pin1 accumulates in Lewy bodies of Parkinson Disease and facilitates formation of α-synuclein inclusions

by Ryo, A., Hirai, A., Nishi, M., Yamaguchi, A., Aoki, I., Togo, T., Suzuki, K., Hirayasu, Y., Nakai, T., Kobayashi, H., Perrem, K., Liou, Y.-C.
Published 2011

Molecular and enzymatic characterization of XMRV protease by a cell-free proteolytic analysis

by Matsunaga, S., Sawasaki, T., Ode, H., Morishita, R., Furukawa, A., Sakuma, R., Sugiura, W., Sato, H., Katahira, M., Takaori-Kondo, A., Yamamoto, N., Ryo, A.
Published 2016

Induction of cells with cancer stem cell properties from nontumorigenic human mammary epithelial cells by defined reprogramming factors

by Nishi, M., Sakai, Y., Akutsu, H., Nagashima, Y., Quinn, G., Masui, S., Kimura, H., Perrem, K., Umezawa, A., Yamamoto, N., Lee, S.W., Ryo, A.
Published 2016

Elevated PIN1 expression by C/EBPα-p30 blocks C/EBPα-induced granulocytic differentiation through c-Jun in AML

by Pulikkan, J.A., Dengler, V., Peer, Zada A.A., Geletu, M., Behre, G., Kawasaki, A., Tenen, D.G., Pasalic, Z., Bohlander, S.K., Ryo, A.
Published 2011

Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration

by Liou, Y.-C., Sun, A., Ryo, A., Zhou, X.Z., Lu, K.P., Bing, G., Yu, Z.-X., Li, X., Huang, H.-K., Hunter, T., Uchida, T., Bronson, R.
Published 2013

The phosphorylation of HIV-1 Gag by atypical protein kinase C facilitates viral infectivity by promoting Vpr incorporation into virions

by Kudoh, A., Takahama, S., Sawasaki, T., Ode, H., Yokoyama, M., Okayama, A., Ishikawa, A., Miyakawa, K., Matsunaga, S., Kimura, H., Sugiura, W., Sato, H., Hirano, H., Ohno, S., Yamamoto, N., Ryo, A.
Published 2016

ASK1 restores the antiviral activity of APOBEC3G by disrupting HIV-1 Vif-mediated counteraction

by Miyakawa K., Matsunaga S., Kanou K., Matsuzawa A., Morishita R., Kudoh A., Shindo K., Yokoyama M., Sato H., Kimura H., Tamura T., Yamamoto N., Ichijo H., Takaori-Kondo A., Ryo A.
Published 2016

Sulfated Polysaccharide, Curdlan Sulfate, Efficiently Prevents Entry/Fusion and Restricts Antibody-Dependent Enhancement of Dengue Virus Infection In Vitro: A Possible Candidate fo...

by Ichiyama, K., Gopala Reddy, S.B., Zhang, L.F., Chin, W.X., Muschin, T., Heinig, L., Suzuki, Y., Nanjundappa, H., Yoshinaka, Y., Ryo, A., Nomura, N., Ooi, E.E., Vasudevan, S.G., Yoshida, T., Yamamoto, N.
Published 2014