Targeting intracellular oncoproteins with antibody therapy or vaccination

by Guo, K., Li, J., Tang, J.P., Tan, C.P.B., Hong, C.W., Al-Aidaroos, A.Q.O., Varghese, L., Huang, C., Zeng, Q.
Published 2014

Engineering the first chimeric antibody in targeting intracellular PRL-3 oncoprotein for cancer therapy in mice

by Guo, K., Tang, J.P., Jie, L., Al-Aidaroos, A.Q.O., Hong, C.W., Tan, C.P.B., Park, J.E., Varghese, L., Feng, Z., Zhou, J., Chng, W.J., Zeng, Q.
Published 2014

PRL-3, a metastasis associated tyrosine phosphatase, is involved in FLT3-ITD signaling and implicated in anti-aml therapy

by Zhou, J., Bi, C., Chng, W.-J., Cheong, L.-L., Liu, S.-C., Mahara, S., Tay, K.-G., Zeng, Q., Li, J., Guo, K., Tan, C.P.B., Yu, H., Albert, D.H., Chen, C.-S.
Published 2014