Estrogenic activity of diarylheptanoids from Curcuma comosa Roxb. requires metabolic activation

by Wipawee Winuthayanon, Kanoknetr Suksen, Chuenchit Boonchird, Aporn Chuncharunee, Mathurose Ponglikitmongkol, Apichart Suksamrarn, Pawinee Piyachaturawat
Published 2018

Diarylheptanoid phytoestrogens isolated from the medicinal plant curcuma comosa: Biologic actions in vitro and in vivo indicate estrogen receptor-dependent mechanisms

by Wipawee Winuthayanon, Pawinee Piyachaturawat, Apichart Suksamram, Mathurose Ponglikitmongkol, Yukitomo Arao, Sylvia C. Hewitt, Kenneth S. Korach
Published 2018

Selective Estrogen Receptor Modulator (SERM)-like Activities of Diarylheptanoid, a Phytoestrogen from Curcuma comosa, in Breast Cancer Cells, Pre-osteoblast Cells, and Rat Uterine...

by Natthakan Thongon, Nittaya Boonmuen, Kanoknetr Suksen, Patsorn Wichit, Arthit Chairoungdua, Patoomratana Tuchinda, Apichart Suksamrarn, Wipawee Winuthayanon, Pawinee Piyachaturawat
Published 2018

The natural estrogenic compound diarylheptanoid (D3): In vitro mechanisms of action and in vivo uterine responses via estrogen receptor α

by Wipawee Winuthayanon, Pawinee Piyachaturawat, Apichart Suksamrarn, Katherine A. Burns, Yukitomo Arao, Sylvia C. Hewitt, Lars C. Pedersen, Kenneth S. Korach
Published 2018

Development of phenotypic and transcriptional biomarkers to evaluate relative activity of potentially estrogenic chemicals in ovariectomized mice

by Sylvia C. Hewitt, Wipawee Winuthayanon, Brianna Pockette, Robnet T. Kerns, Julie F. Foley, Norris Flagler, Elizabeth Ney, Apichart Suksamrarn, Pawinee Piyachaturawat, Pierre R. Bushel, Kenneth S. Korach
Published 2018